Clinical Trials Logo

Clinical Trial Summary

The aim of the iSPOT-A study is to:

1. identify brain, genetic and cognitive markers of Attention Deficit/Hyperactivity Disorder, and

2. identify brain, genetic and cognitive markers that predict treatment response to short-acting methylphenidate in children and adolescents diagnosed with Attention Deficit/Hyperactivity Disorder.


Clinical Trial Description

This is a multi-center, open-label effectiveness trial to identify objective indicators of treatment response in ADHD subjects (versus healthy controls) using cognitive and brain function measures, brain structure and genetic measures in subjects diagnosed with ADHD.

At least 672 naïve and treatment experienced subjects with ADHD will be enrolled from approximately 10 primary care centers. These patients are to be outpatients.

In addition, up to 672 healthy (non-ADHD) control subjects will be recruited who match the enrolled ADHD subjects in race, age, gender and years of education. ;


Study Design


Related Conditions & MeSH terms

  • Attention Deficit Disorder with Hyperactivity
  • Attention Deficit/Hyperactivity Disorder
  • Disease
  • Hyperkinesis

NCT number NCT00863499
Study type Interventional
Source BRC Operations Pty. Ltd.
Contact
Status Active, not recruiting
Phase Phase 4
Start date October 2009
Completion date December 2019

See also
  Status Clinical Trial Phase
Recruiting NCT05741307 - Effect of a Self-hypnosis on Attention Disorders and Anxiety in Children With Attention Deficit/Hyperactivity Disorder N/A
Not yet recruiting NCT06133231 - Optimizing Research With Diverse Families N/A
Completed NCT02286349 - Non Invasive Brain Stimulation Effects on Attentional Performance in ADHD Adults N/A
Completed NCT00214981 - Evaluate the Safety and Efficacy of Modafinil in Children and Adolescents With ADHD Phase 3
Active, not recruiting NCT04189536 - An SMS Intervention to Improve Adherence to Stimulant Medications in Adults With ADHD N/A
Recruiting NCT02433145 - Explore the Association Between Neuropsychological Functions and ADHD Diagnosis and Comorbid Using Longitudinal Study in Preschool Children N/A
Completed NCT01263548 - To Evaluate the Safety and Metabolic Profile of Vyvanse for the Treatment of ADHD in Euthymic Adults With Bipolar I/II Disorder N/A
Completed NCT02728011 - Pilot Trial Comparing Computerised Cognitive Exercises to Tetris in Adolescents With ADHD N/A
Completed NCT01275378 - Comparative Effectiveness Research for Two Medical Home Models for Attention Deficit Hyperactivity Disorder N/A
Not yet recruiting NCT00945971 - Exercise Effects in Children With Attention Deficit Hyperactivity Disorder N/A
Active, not recruiting NCT04999982 - Pilot Testing PREschooler Care, Community Resources, Advocacy, Referral, Education (PRE-CARE) N/A
Completed NCT01259492 - Efficacy and Safety Study of Methylphenidate Hydrochloride Extended Release in Adults With Childhood-onset Attention Deficit/Hyperactivity Disorder (ADHD) Phase 3
Recruiting NCT05721235 - A Safety/Tolerability and PK Study With Azstarys® in Children With ADHD Phase 4
Active, not recruiting NCT04189575 - A Text Messaging (SMS) Intervention to Improve Adherence to Stimulant Medication in Adults With ADHD in the Primary Care Setting N/A
Active, not recruiting NCT05685732 - An Efficacy and Safety Study w/ Azstarys® in Children With ADHD Phase 4
Completed NCT02558790 - L-Threonic Acid Magnesium Salt (L-TAMS) in ADHD Phase 2
Recruiting NCT02205268 - Near Infrared Spectroscopy Neurofeedback Training for ADHD N/A
Recruiting NCT00946582 - The Therapeutic Effects of Barkley's Parenting Management Program for Taiwanese School-Aged Children With Attention Deficit/Hyperactivity Disorder (ADHD) Phase 1
Completed NCT00267605 - Strongest Families (Formerly Family Help Program): Pediatric Attention Deficit/Hyperactivity Disorder Phase 2
Recruiting NCT02017483 - Explore the Association Between the Emotion Recognition and the Attention Processing Under the Emotional Stimuli in ADHD N/A