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Response of Intracardiac Thrombus to Anticoagulants in Patients With Non-valvular Atrial Fibrillation (LYSIS) — LYSIS  

Atrial Fibrillation Clinical Trial

Official title:
Response of Intracardiac Thrombus to Anticoagulants in Patients With Non-valvular Atrial Fibrillation (LYSIS): an Investigator-initiated, National, Multicenter, Retrospective-prospective, Observational Cohort Study

Clinical Trial Summary

This study aims to analyze changes in the immune status, metabolic status, and host microbiome community structure in non-valvular atrial fibrillation patients with intracardiac thrombus. Additionally, the study aims to analyze factors that influence the responsiveness and occurrence of adverse events related to anticoagulant therapy.

Clinical Trial Description

The researcher-initiated clinical cohort study is a national multicenter, retrospective-prospective study of non-valvular atrial fibrillation patients with intracardiac thrombus, based on molecular biology and multi-omics analysis. The study aims to analyze the changes in the body's immune status, metabolic status, and host microbiome community structure, as well as to analyze the factors that influence the responsiveness of intracardiac thrombus to anticoagulant therapy. The study also evaluates the occurrence of adverse events related to anticoagulation in these patients. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT06141538
Study type Observational
Source First Affiliated Hospital Xi'an Jiaotong University
Contact Guoliang Li
Phone +8613759982523
Email liguoliang_med@163.com
Status Not yet recruiting
Phase
Start date December 31, 2024
Completion date December 31, 2030
View Details
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