Clinical Usefulness of Virtual Ablation Guided Catheter Ablation of Atrial Fibrillation: Prospective Randomized Study

Atrial Fibrillation Clinical Trial

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT02171364
• Other study ID #: 4-2013-0536
• Status: Completed
• Phase: N/A
• Start date: August 2014
• Est. completion date: September 1, 2015

Study information

• Verified date: March 2019
• Source: Yonsei University
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Radiofrequency catheter ablation is highly effective in the treatment of patients with persistent atrial fibrillation. In order to decrease the recurrence rate after catheter ablation, the investigators propose to apply 'virtual' ablation on patient-specific atria by simulating 3D atrial computer model. The investigators will test with five different set of ablation methods and find successful methods for a specific patient. Then, this result will be compared to empirical catheter ablation result by randomly controlled trial.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 40
• Est. completion date: September 1, 2015
• Est. primary completion date: September 1, 2015
• Accepts healthy volunteers: No
• Gender: All
• Age group: 19 Years and older

Eligibility

Inclusion Criteria:

• Diagnosis of AF patients who performed catheter ablation of atrial fibrillation due to uncontrolled pulse rate by anti-arrhythmic drug therapy.

Exclusion Criteria:

• AF patients who have severe heart deformations or blood problems.

• The patients who had been performed catheter ablation of atrial ablation.

• The patients who missed out to recording of 3D CT, echo and electrocardiography.

Related Conditions & MeSH terms

• Atrial Fibrillation

Intervention

Procedure:
• Virtual ablation in based 3D CT of patient who diagnosed AF

• conventional ablation based on physician's personal experience

Locations

Country	Name	City	State
Korea, Republic of	Severance Hospital	Seoul

Sponsors (1)

Lead Sponsor	Collaborator
Yonsei University

Country where clinical trial is conducted

Korea, Republic of, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	change of hospitalization rate		1, 3, 6, 12, 18 and 24 months after catheter ablation and every 6 months thereafter.
Secondary	occurence of cardiovascular disease		6 months
Secondary	recurrence of AF		6 months