Exercise Performance in Patients With Atrial Fibrillation

Atrial Fibrillation Clinical Trial

— AF-CPX  

Official title:

Exercise Performance in Patients With Atrial Fibrillation: Usefulness of Cardiopulmonary Exercise Test

Clinical Trial Details — Status: Not yet recruiting

Administrative data

• NCT number: NCT01943981
• Other study ID #: OC13OISI0099
• Status: Not yet recruiting
• Phase: N/A
• First received: September 12, 2013
• Last updated: September 12, 2013
• Start date: September 2013

Study information

• Verified date: September 2013
• Source: Incheon St.Mary's Hospital
• Contact: n/a
• Is FDA regulated: No
• Health authority: Korea (the Republic of): the Clinical Research Cordinating Center (CRCC) of the Catholic University Center
• Study type: Observational [Patient Registry]

Clinical Trial Summary

Heart failure and stroke are the two major complication of atrial fibrillation. Current treatment for atrial fibrillation is so focused to stroke prevention, but the risk assessment for heart failure is less highlighted. The most of patients with atrial fibrillation have cardiac functional limitation of variable degree. We hypothesize that the exercise test would reveal the subclinical cardiac dysfunction, and might be helpful to classify the patients with atrial fibrillation according to their exercise capacity real cardiac function.

Recruitment information / eligibility

• Status: Not yet recruiting
• Enrollment: 50
• Est. primary completion date: February 2015
• Accepts healthy volunteers: No
• Gender: Both
• Age group: 30 Years to 80 Years

Eligibility

Inclusion Criteria:

• Nonvalvular chronic atrial fibrillation

• Left ventricular ejection fraction >40%

Exclusion Criteria:

• Acute decompensated heart failure within 30 days

• unstable hemodynamic status

• Significant coronary artery disease

• Any condition interfering sufficient exercise

• Valvular stenosis or regurgitation of moderate or severe degree

• Obstructive or restrictive lung disease of moderate or severe degree

• Active malignancy

Study Design

Observational Model: Case-Only, Time Perspective: Prospective

Related Conditions & MeSH terms

• Atrial Fibrillation

Locations

Country	Name	City	State
Korea, Republic of	Incheon St.Mary's Hospital	Incheon

Sponsors (1)

Lead Sponsor	Collaborator
Incheon St.Mary's Hospital

Country where clinical trial is conducted

Korea, Republic of, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Exercise response patterns of heart rate and oxygen uptake		At baseline	No
Secondary	Composite cardiovascular events (all death, admission of heart failure, stroke/thromboembolism)		Up to 2 years	No