Atrial Fibrillation Clinical Trial
Official title:
Observational Prospective Case-control Study on Prevalence and Impact of Subclinical Hyperthyroidism in Patients Undergoing Atrial Fibrillation Ablation
Overt hyperthyroidism (so-called "goiter" in lay language) is a hormonal disturbance that is
known to increase the risk of atrial fibrillation (a common heart arrhythmia with
potentially severe consequences) in some patients. Previous research has indicated that even
slight elevations in thyroid hormone levels - so called subclinical hyperthyroidism - may
increase this risk. When atrial fibrillation and overt hyperthyroidism are found
simultaneously in a patient, the hormonal imbalance must be treated first in order to later
resolve the arrhythmia. It is unclear whether this strategy holds true for subclinical
hyperthyroidism. Our two hypotheses are: 1) Subclinical hyperthyroidism is more prevalent in
patients admitted for atrial fibrillation ablation than in the population as a whole, and 2)
Patients with subclinical hyperthyroidism and atrial fibrillation benefit less from ablation
than others.
As a control group, we have chosen patients admitted for ablation of AV-nodal Reentry
Tachycardia at the same clinics as the cases. No correlation has ever been shown between
AV-nodal Reentry Tachycardia and hyperthyroidism.
n/a
Observational Model: Case Control, Time Perspective: Prospective
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