Atrial Fibrillation Clinical Trial
Official title:
Effect of Thoracic Epidural Analgesia for Thoracic Surgery on Arrhythiogenesis
Thoracic epidural anesthesia and analgesia for patients undergoing lung resection can reduce the occurrence of AF if it is continued for six postoperative days instead of just three.
THEA is considered a very effective technique of providing intra and post-operative
analgesia for thoracic surgical procedure and it seems that can also be effective in
reducing the incidence of postoperative AF in patients undergoing lung resection.
Nevertheless the timing of stopping the epidural analgesia and its further substitution with
other therapies, remains unclear.
In this study patients who are scheduled for lung resection surgery will undergo the surgery
under combined general anesthesia with volatile anesthetics and thoracic epidural
anesthesia.
Immediately after surgery the patients will be divided into two groups:
- those who will receive thoracic epidural analgesia for 6 days
- those who will receive thoracic epidural analgesia for 3 days and will then switch to
intravenous morphine for another 3 days
All the patients will be monitored daily for arrythmias
;
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Prevention
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