Effect of 3 Years of Exercise on Development of Atrial Fibrillation

Atrial Fibrillation Clinical Trial

Official title:

Effect of 3 Years of Exercise on Development of Atrial Fibrillation - A "Generation 100" Substudy

Clinical Trial Details — Status: Active, not recruiting

Administrative data

• NCT number: NCT01680302
• Other study ID #: 2012/978b-2
• Status: Active, not recruiting
• Phase: N/A
• Start date: September 2012
• Est. completion date: June 2026

Study information

• Verified date: September 2022
• Source: Norwegian University of Science and Technology
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

This is a substudy of "Generation 100". In that study, 4000 healthy persons between 70 and 75 will be randomised to a moderate intensity training group, a high intensity training group or control group, with 3 years of exercise. The investigators will follow these persons and register all who develop atrial fibrillation during these 3 years, and at follow-up after ended intervention to see if there is differences in the number of persons who develop atrial fibrillation in the 3 groups.

Recruitment information / eligibility

• Status: Active, not recruiting
• Enrollment: 1567
• Est. completion date: June 2026
• Est. primary completion date: June 2023
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 70 Years to 75 Years

Eligibility

Inclusion Criteria:

• Participating in the "Generation 100" study

Exclusion Criteria:

-

Related Conditions & MeSH terms

• Atrial Fibrillation

Intervention

Behavioral:
• High intensity exercise

• Moderate intensity exercise

• Control
Advised to follow current guidelines for physical activity, but exercise on their own.

Locations

Country	Name	City	State
Norway	Norwegian University of Science and Technology	Trondheim

Sponsors (2)

Lead Sponsor	Collaborator
Norwegian University of Science and Technology	St. Olavs Hospital

Country where clinical trial is conducted

Norway, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Number of persons who develop atrial fibrillation during the 3 year intervention period	People who already have the diagnosis before randomisation will not be counted.	3 years
Secondary	Number of persons who develop atrial fibrillation during the 6 years after randomisation		6 years