Atrial Fibrillation Clinical Trial
Official title:
A Randomized Controlled Prospective Trial of Warfarin Versus Aspirin for Stroke Prevention in Patients With Atrial Fibrillation and Chronic Kidney Disease
In this study, the investigators examine whether aspirin or warfarin is useful for atrial fibrillation patients with chronic kidney disease.
randomised open labelled prospective study
We enroll patients with CHADS2 score 1 non-valvular AF with chronic kidney disease, and
analyze all thromboembolic event or major bleeding event during follow-up period. Warfarin
group take dose adjusted warfarin (target INR 2.0-3.0) and aspirin group take aspirin 100mg
daly.
Thromboembolic events: Ischemic stroke or systemic arterial occlusion Major bleeding:
gastrointestinal bleeding or intracranial bleeding (code 430, code 431, code 432 by ICD-9-CM
codes)
-> Only the first event of each case will be used for the analysis
;
Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Prevention
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