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Atrial Fibrillation clinical trials

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NCT ID: NCT03091205 Withdrawn - Atrial Fibrillation Clinical Trials

Proper Extent of Maze Intercaval Lesion

Maze
Start date: April 15, 2018
Phase:
Study type: Observational

It's hypothesized that a mean and range distance from the cavo-atrial junction to the area where there is complete loss of conductive tissue can be measured to better inform surgeons performing the Cox-Maze procedure. A patient scheduled for any cardiac surgery where visualization and mapping of cavo-atrial junction is possible could be entered into the study if they meet the inclusion/exclusion requirements.

NCT ID: NCT03002740 Withdrawn - Clinical trials for Non-valvular Atrial Fibrillation

Bleeding Events and Oral Anticoagulant Treatment in Non-Valvular Atrial Fibrillation

Start date: January 31, 2016
Phase:
Study type: Observational

In a population of patients with non-valvular atrial fibrillation (NVAF), and treated with oral anticoagulants (OAC) in routine clinical practice in England, this study will describe patients treated with each OAC, and to estimate and compare event rates of treatment discontinuation, bleeding, and healthcare resource utilisation (HCRU) across OAC treatments.

NCT ID: NCT02954380 Withdrawn - Atrial Fibrillation Clinical Trials

The Comparative Efficacy of the Zio Patch vs Implantable Loop Recorder in Atrial Fibrillation

ALERT-AF
Start date: November 2016
Phase: N/A
Study type: Interventional

The aim of our study is to investigate if LTCM's are superior to implantable loop recorders in detecting atrial fibrillation after pulmonary vein isolation. This study will provide insights on a possible alternative for detection of arrhythmia.

NCT ID: NCT02900404 Withdrawn - Atrial Fibrillation Clinical Trials

Verification of XAPPORT: a Decision Support App for Physicians Used for Patients Anticoagulated With Rivaroxaban in Terms of Anticoagulation Management in Elective Surgery: Verification Process of Medical Decision Algorithm

VeriXAPPORT
Start date: February 15, 2017
Phase: N/A
Study type: Observational

This study shall determine whether XAPPORT - a mobile device app based on different guidelines, the summary of product characteristics of rivaroxaban, and clinical facts and practice - provides adequate guidance to physicians attending patients undergoing elective surgery, who have to interrupt treatment with rivaroxaban for surgery, in deciding how to approach the pre- and postoperative management of anticoagulation.

NCT ID: NCT02758002 Withdrawn - Atrial Fibrillation Clinical Trials

Inhibition of Atrial Fibrillation by Elimination of Transitional Mechanisms

TRANS AF
Start date: January 28, 2016
Phase: N/A
Study type: Interventional

There is growing awareness of the importance of electrical rotors to the maintenance of atrial fibrillation (AF). Recent work in our laboratory has found that AF evolves over time, from rapid, focal activation, next to transitional rotors, and finally to stable, long duration rotors, whose locations are frequently separate from the transitional rotor sites. This project will test the hypothesis that mapping and ablation of the transitional rotors sites may prevent atrial fibrillation from progressing to sustained atrial fibrillation, and therefore increase the AF initiation threshold. The investigators will test this hypothesis during clinically-indicated electrophysiology study prior to ablation of symptomatic AF.

NCT ID: NCT02666729 Withdrawn - Atrial Fibrillation Clinical Trials

Use of a Novel Contact Force Sensing Catheter for AF Ablation - Impact of TactiCath on Dormant Conduction Across the Pulmonary Veins

FORMIDIBLE
Start date: July 2016
Phase: N/A
Study type: Observational

The purpose of this study is to collect information about the success rate of atrial fibrillation (AF) ablation procedures using the contact force data from the TactiCath Quartz ablation catheter.

NCT ID: NCT02614521 Withdrawn - Atrial Fibrillation Clinical Trials

Predictive Factors for Successful Outcome After Pulmonary Veins Ablation to Treat Paroxysmal Atrial Fibrillation

Start date: January 2017
Phase:
Study type: Observational

Atrial fibrillation is the most common serious abnormal heart rhythm affecting about 2% to 3% of the population, being associated with a 1.5- to 1.9-fold higher risk of death. Patients with paroxysmal AF in whom antiarrhythmic drug therapy does not elicit a response are potential candidates for RF ablation of AF. The success rate of RF ablation in the treatment of AF varies depending on the type and duration of AF (ie, paroxysmal vs persistent), structural remodeling of the heart, co-morbidities and the technique of the cardiac electrophysiologist, but it usually ranges from 60-80% over 1-2 years of follow-up. To study and predict the successful outcome of RF ablation is of great clinical importance. Moreover, the detection of predictive factors for successful outcome may alter the therapeutic strategy determining a subgroup of patients in the need of more invasive management.

NCT ID: NCT02582190 Withdrawn - Atrial Fibrillation Clinical Trials

COlchicine for the Prevention of Post Electrical Cardioversion Recurrence of AF

COPPER-AF
Start date: December 2, 2017
Phase: Phase 3
Study type: Interventional

There is substantial evidence linking inflammation to the initiation and perpetuation of AF. Although the precise mechanism by which inflammation contributes to the development of AF remains unclear, it has been proposed that inflammation may lead to "atrial myocarditis" with subsequent electrical and structural changes involving both atrial myocytes and extracellular matrix, leading finally to initiation and maintenance of AF. The high incidence of AF in post-operative cardiac surgeries, a state of intense inflammatory process, points out this association. Similarly, in non operative AF, inflammation appears to play a prominent role in both etiology and maintenance of AF. Indeed an increase of inflammatory markers to both paroxysmal and persistent AF was shown by numerous studies.

NCT ID: NCT02534532 Withdrawn - Atrial Fibrillation Clinical Trials

Atrial Fibrillation Screening With a Smartphone Device and iECG Application

AFScreenCol
Start date: October 2015
Phase: N/A
Study type: Observational

Question: Can atrial fibrillation (AF) cases in patients ≥ 65 years be easily detected in a primary healthcare environment using a smartphone device and iECG application as an opportunistic screening tool? Objectives: Detection of AF through cardiac rhythm abnormalities in patients ≥65 years old in an opportunistic screening program using a smartphone device/application 1. Define the predictable value of the smartphone device with electrocardiogram (ECG) confirmation to detect AF in patients 65 years and older 2. Correlate screened patients cardiovascular risk profile and those that register cardiac rhythm irregularities for a better description of the general characteristics of Colombian population

NCT ID: NCT02450682 Withdrawn - Atrial Fibrillation Clinical Trials

Apixaban in Patients Who Undergo CIED Procedure- Randomized Pilot Study

Apixaban
Start date: February 2016
Phase: Phase 2
Study type: Interventional

This study is being done to determine if apixaban is more safe, when compared to warfarin, at reducing the risk of bleeding during CIED procedures.