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Atopic Dermatitis clinical trials

View clinical trials related to Atopic Dermatitis.

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NCT ID: NCT06277245 Recruiting - Atopic Dermatitis Clinical Trials

A Phase 3 Study of LNK01001 Capsule in Subjects With Moderate to Severe Atopic Dermatitis.

Start date: February 6, 2024
Phase: Phase 3
Study type: Interventional

This is a randomized, double-blind study comparing LNK01001 to placebo in participants with moderately to severely atopic dermatitis who were candidates for systemic therapy (ie, patients with a history of inadequate response to topical treatments, those who were using a systemic treatment, or those for whom topical treatments are otherwise medically inadvisable). The objective of this study is to evaluate the efficacy and safety of LNK01001 in adult patients with moderate to severe AD who are candidates for systemic therapy.

NCT ID: NCT06268860 Recruiting - Atopic Dermatitis Clinical Trials

A Study to Assess Bioavailability of Rocatinlimab (AMG 451) Vial and Prefilled Syringe in Healthy Participants

Start date: February 15, 2024
Phase: Phase 1
Study type: Interventional

The primary objective of the study is to evaluate the pharmacokinetics (PK) of rocatinlimab given as a single subcutaneous (SC) dose in a vial compared to a prefilled syringe in healthy participants.

NCT ID: NCT06268847 Recruiting - Atopic Dermatitis Clinical Trials

Efficacy of Marine By-product Hydrolysate on the Reduction of Atopic Dermatitis Symptoms

Start date: January 9, 2024
Phase: N/A
Study type: Interventional

This interventional, double-blind, randomized, placebo-controlled study aims to evaluate the effect of a marine by-product hydrolysate supplementation on the reduction of atopic dermatitis symptoms.

NCT ID: NCT06259669 Recruiting - Atopic Dermatitis Clinical Trials

Study to Compare Maternal, Fetal, and Infant Outcomes of Women With Mild to Moderate Atopic Dermatitis Exposed to Ruxolitinib Cream During Pregnancy With an Unexposed Control Population

OPERA-1
Start date: September 13, 2023
Phase:
Study type: Observational

This observational (enrollment into the registry while the pregnancy is ongoing) study is being conducted to compare the frequency of major congenital malformation (MCM)s among infants of women exposed to ruxolitinib cream during pregnancy with infants of women not exposed to ruxolitinib cream during pregnancy.

NCT ID: NCT06238817 Recruiting - Atopic Dermatitis Clinical Trials

A Study to Evaluate the Efficacy, and Safety Study of Ruxolitinib Cream in Adults With Moderate Atopic Dermatitis

TRuE-AD4
Start date: April 26, 2024
Phase: Phase 3
Study type: Interventional

This study is being conducted to establish the efficacy of ruxolitinib cream in participants with moderate AD who had an inadequate response to, or are intolerant to, or contraindicated to topical corticosteroid (TCS)s and topical calcineurin inhibitor (TCI)s.

NCT ID: NCT06224192 Recruiting - Atopic Dermatitis Clinical Trials

A Study With Self-administered Rocatinlimab in Adolescent and Adult Participants With Moderate-to-severe AD

ROCKET-Outpost
Start date: April 2, 2024
Phase: Phase 3
Study type: Interventional

The primary objective of this study is to assess successful self-administration of rocatinlimab subcutaneous using devices for injection at home.

NCT ID: NCT06194045 Recruiting - Atopic Dermatitis Clinical Trials

Nutritional Study to Determine the Effect of Fish Oil on Atopic Dermatitis

CetoSkin
Start date: December 1, 2023
Phase: N/A
Study type: Interventional

Atopic Dermatitis is associated with pronounced changes in the lipid composition in the skin. The lipid changes are influenced by and contributing to both the inflammatory circuit and the impaired barrier as well as changes in the skin microbiome This nutritional study will investigate the effect of long-chain monounsaturated fatty acid Cetoleic acid on atoptic dermatitis. Earlier studies have shown a anti-inflammatory effect of celoteic acid.

NCT ID: NCT06176040 Recruiting - Atopic Dermatitis Clinical Trials

A Study of TAVO101 in Atopic Dermatitis Patients

Start date: March 15, 2024
Phase: Phase 2
Study type: Interventional

This is a Phase 2 pilot study to examine the preliminary efficacy, safety and PK of TAVO101 in adult patients with severe AD.

NCT ID: NCT06169527 Recruiting - Atopic Dermatitis Clinical Trials

A Long-term Data Collection Study of Participants in France Aged 6 Years Old or More With Atopic Dermatitis Receiving Dupilumab

DUPILAB
Start date: November 28, 2023
Phase:
Study type: Observational

This is a long-term study to collect data over 3 years in order to find out what is likely to happen in the future regarding participants 6 years of age and older who receive dupilumab for Atopic Dermatitis (AD) commonly known as Eczema, and to characterize real-world effectiveness, safety and use patterns of dupilumab in real world setting in France. Patients will be invited to participate if initiating treatment with dupilumab for AD according to French-specific prescribing information. The decision of initiation of the treatment is independent to the study's participation. The study will be conducted in approximately 50 centers in France to evaluate a representative sample of patients treated in France. At each participating site, all AD participants who receive an initial prescription for dupilumab will be invited to participate in this study, until the enrollment goal is achieved.

NCT ID: NCT06136767 Recruiting - Atopic Dermatitis Clinical Trials

Registry for Systemic Eczema Treatments

RESET
Start date: January 17, 2024
Phase:
Study type: Observational [Patient Registry]

The Registry for Systemic Eczema Therapies (RESET) registry is a database and biospecimen repository for patients with pediatric-onset atopic dermatitis (AD) who have used or will initiate any systemic treatment(s) for AD. The goal of the registry is to enable more efficient research recruitment and data collection as well as timely notification to enrollees about newly FDA-approved treatments for AD.