Atherosclerosis Clinical Trial
Official title:
Standardization of Normal Parameters of Cranial Vessels by Using Extra and Trans Cranial Vascular Duplex Among Egyptian Population
the study will be carried out to standardize normal parameters of vascular duplex ultrasound of the cranial vessels in the Egyptian population.
Atherosclerosis is a major cause of ischemic stroke and a significant proportion of strokes
are thromboembolic in nature, arising from atherosclerotic plaques. Several studies have
reported racial differences in the severity and distribution of carotid atherosclerosis. In
the United States and Western communities, Extra-cranial carotid artery disease was estimated
to be responsible for 20—30% of strokes. Little is known about the prevalence and
distribution of carotid disease among the populations in the developing countries.
Vascular duplex ultrasound is a useful, cheap and available diagnostic tool for assessing
cranial vascular disease. Duplex ultrasound can be highly reliable with proper technique,
without the risk of radiation in other imaging modalities, is well tolerated by all patients
including those who are claustrophobic in MRI machines, and has much less risks compared to
conventional angiography studies.
Although vascular duplex has been used for years yet there is little researches had been done
on normal population in the developing countries to collect results and compare it to the
parameters that was collected and reviewed in the western developed populations.
The parameters that would be used in this study include both the data collected by static and
dynamic duplex scan which are the intimal-medial thickness, the vessels' diameter, peak flow
velocity and peak flow volume both systolic and diastolic for either extra- or intra-cranial
vessels.
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