Imaging of Atherosclerosis With 68Ga-MSA

Status Completed

Clinical Trial Summary

Despite of intensive efforts, no specific ath¬erosclerosis-targeting agent labeled with positron emitter is not yet available. Fortunately, some scientists made the major advance in the field of clinical atherosclerosis molecular imaging by the metabolic PET reporter agent 18F(fluorine-18)-FDG(Fludeoxyglucose) applied to noninvasively image plaque macrophages in carotid arteries. However, coronary and cerebral arterial segments remain uninterpretable due to metabolic property of 18F-FDG. Applying the character of the terminal mannose residues of MSA binding with the mannose receptors of macrophages in atherosclerosis, we investigate whether 68Ga-MSA can be a novel agent for non-invasive molecular imaging of atherosclerotic lesion in PET.

Clinical Trial Description

n/a

Study Design

Observational Model: Case Control, Time Perspective: Prospective

Related Conditions & MeSH terms

Atherosclerosis
Noninvasive Imaging of Atherosclerosis

Clinical Trial Details

NCT number	NCT01889693
Study type	Observational
Source	Korea University
Contact
Status	Completed
Phase	N/A
Start date	August 2012
Completion date	August 2013

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