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NCT01701830 Clinical Trial

Serum Omentin-1 and Carotid Atherosclerosis In Non-Diabetic Chronic Kidney Disease

Atherosclerosis Clinical Trial

Official title:
The Relationship Between Serum Omentin-1 and IL-6 and Carotid Atherosclerosis In Non-Diabetic Chronic Kidney Disease

Clinical Trial Details — Status: Recruiting

Administrative data
NCT number NCT01701830
Other study ID # 2012/02
Secondary ID
Status Recruiting
Phase N/A
First received October 3, 2012
Last updated October 4, 2012
Start date October 2012
Est. completion date May 2013

Study information
Verified date October 2012
Source Kocaeli Derince Education and Research Hospital
Contact n/a
Is FDA regulated No
Health authority Turkey: Ministry of Health
Study type Observational

Clinical Trial Summary

The aim of the study is to evaluate whether a low level of serum omentin-1 is associated with carotid atherosclerosis and mediated by inflammation.

Description:

Atherosclerotic cardiovascular disease is markedly increased in chronic kidney disease. There are a lot of risk factor, along with conventional risk factors. Serum onemtin-1 is a adipokine and suggested as a new marker for vascular disease.It has some anti-atherogenic properties. Studies investigating serum omentin-1 level have usually conducted in patients with diabetes mellitus.

Recruitment information / eligibility
Status Recruiting
Enrollment 85
Est. completion date May 2013
Est. primary completion date
Accepts healthy volunteers Accepts Healthy Volunteers
Gender Both
Age group 18 Years to 75 Years
Eligibility Inclusion Criteria:

- between ages of 18 - 65 years old chronic kidney disease of stage 3-4

Exclusion Criteria:

- Chronic kidney disease of stage 5

- The history of ischemic cardiovascular disease (myocardial infarction, unstable angina, stroke, peripheral artery disease, or cardiovascular revascularization)

- Severe heart failure

- Stage 2 hypertension

- Diabetes mellitus

- Corticosteroid therapy

- Severe hepatic disease

- Smoking

- Inflammatory disease

- Acute infectious disease

- Malignancy

Study Design

Observational Model: Case Control, Time Perspective: Cross-Sectional

Related Conditions & MeSH terms

Locations
Country Name City State
Turkey Department of Nephrology, Check-up Clinic,Kocaeli Derince Education and Traning Hospital Izmit Kocaeli

Sponsors (1)
Lead Sponsor Collaborator
Kocaeli Derince Education and Research Hospital

Country where clinical trial is conducted

Turkey, 

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