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NCT01548274 Clinical Trial

Impact of Sarpogrelate in the Function of Endothelial Progenitor Cells

Atherosclerosis Clinical Trial

Official title:
Impact of Sarpogrelate in the Function of Endothelial Progenitor Cells

Clinical Trial Details — Status: Recruiting

Administrative data
NCT number NCT01548274
Other study ID # AGU-65
Secondary ID
Status Recruiting
Phase N/A
First received March 5, 2012
Last updated March 5, 2012
Start date October 2010
Est. completion date October 2012

Study information
Verified date March 2012
Source Aichi Gakuin University
Contact n/a
Is FDA regulated No
Health authority Japan: Ministry of Health, Labor and Welfare
Study type Interventional

Clinical Trial Summary

The purpose of this study is to evaluate the effects of Sarpogrelate in endothelial progenitor cells of patients with atherosclerosis.

Description:

Endothelial progenitor cells play an important role in vasculogenesis and vascular repair. Sarpogrelate, a inhibitor of HT2A, is used an an anti-platelet drug, however, a direct effect in vascular cells is supposed.

Recruitment information / eligibility
Status Recruiting
Enrollment 20
Est. completion date October 2012
Est. primary completion date October 2012
Accepts healthy volunteers No
Gender Both
Age group 20 Years and older
Eligibility Inclusion Criteria:

- Patients with atherosclerosis

Exclusion Criteria:

- Patients with high risk of bleeding

- Patients with pregnancy

- Patients with allergic reaction of Salpogrelate

Study Design

Endpoint Classification: Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment

Related Conditions & MeSH terms

Intervention

Drug:
• Sarpogrelate
Sarpogrelate 300mg/day

Locations
Country Name City State
Japan Aichi-Gakuin University Nagoya Aichi

Sponsors (1)
Lead Sponsor Collaborator
Aichi Gakuin University

Country where clinical trial is conducted

Japan, 

Outcome
Type Measure Description Time frame Safety issue
Primary The number and function of endothelial progenitor cells 3 months No
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