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Atelectasis clinical trials

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NCT ID: NCT02548416 Completed - Atelectasis Clinical Trials

Peroperative Use of Positive End-expiratory Pressure Prevents Formation of Atelectasis as Studied by Computerised Tomography at End of Surgery

Start date: November 2015
Phase: N/A
Study type: Interventional

Atelectasis is common during and after general anaesthesia and a number of interventions have been suggested in order to prevent their formation. The use of Positive End Expiratory Pressure (PEEP) during general anaesthesia has in recent years been questioned. The investigators hypothesize that the use of PEEP as a single intervention improves oxygenation and prevents atelectasis as investigated by computed tomography compared to a control group with zero PEEP.

NCT ID: NCT02523755 Completed - Pregnancy Clinical Trials

Evaluation of Regional Distribution of Ventilation During Labor With or Without Epidural Analgesia

Start date: September 2015
Phase: Phase 4
Study type: Interventional

With an efficient epidural analgesia the physiological effects of pain are disabled during labor. Pain may cause an increase of minute volume, oxygen consumption and a decrease of paCO2 (Arterial CO2 pressure). The study will evaluate the lung function before and after labor with and without epidural analgesia. With more efficient breathing, the occurence of atelectasis should be reduced; this effect will be investigated in these settings for the first time with the electrical impedance tomography, which is a completely non-invasive measure.

NCT ID: NCT02450825 Completed - Pneumonia Clinical Trials

Comparison of Three Scores for Ultrasound Assessment and Monitoring of Pulmonary Aeration

Start date: July 2015
Phase: N/A
Study type: Interventional

This study is designed to compare three ultrasound-based aeration scores that were previously validated in specific populations, and to assess their correlation with computed tomographic measurement of pulmonary aeration in a population with different pathologies. Hypothesis: The "Loss of Aeration Score" will be more accurate than a simplified version and another widely used score, the "Lung Ultrasound Score".

NCT ID: NCT02419196 Completed - Clinical trials for Respiratory Insufficiency

Perioperative Change of Regional Ventilation During Spontaneous Breathing

Start date: January 2015
Phase: N/A
Study type: Observational

Perioperative changes in regional ventilation by pulmonary electrical impedance tomography and spirometry will be investigated in patients at risk for postoperative pulmonary complications. Those patients undergo abdominal and limb operations. In a pilot study arm electrical impedance tomography is tested in patients receiving osteosynthesis of serial rib fractures.

NCT ID: NCT02232841 Completed - Clinical trials for Acute Respiratory Distress Syndrome

Electrical Impedance Imaging of Patients on Mechanical Ventilation

Start date: September 2014
Phase: N/A
Study type: Observational

The goal of this study is to evaluate the sensitivity and specificity of Electrical Impedance Tomography (EIT) as a bedside diagnostic tool for lung pathologies in patients who are mechanically ventilated. In electrical impedance tomography low amplitude, low frequency current is applied on electrodes, and the resulting voltage is measured and used to computed the electrical properties of the interior of the chest as they change in time. The computed properties are used to form an image, which can then be used for monitoring and diagnosis.

NCT ID: NCT02216006 Completed - Atelectasis Clinical Trials

High Fresh Gas Flow After Intubation

Start date: September 2014
Phase: N/A
Study type: Interventional

Atelectasis is common during and after general anesthesia. Atelectasis develops early if preoxygenation with 100% oxygen is used and continuously used during induction until endotracheal intubation. The investigators hypothesize that a rapid anti-preoxygenation maneuver immediately after confirming a successful intubation, reduces the area of atelectasis as investigated by computed tomography compared to a standard procedure.

NCT ID: NCT02168387 Completed - Atelectasis Clinical Trials

Efficacy of Percussive Ventilation Therapy (MetaNeb ®) Compared With Mucolytic Agents for Atelectasis in the Mechanically Ventilated Pediatric Patient

Start date: December 2010
Phase: Phase 4
Study type: Interventional

The purpose of this study is to evaluate whether a therapy that uses a machine called a continuous high frequency oscillator (CHFO) is more successful at removing mucus than medications that thin out the mucus.

NCT ID: NCT02117908 Completed - Lung Cancer Clinical Trials

Study of the Application of CPAP to Reduce Complications and Improve Lung Cancer Ablation Radiofrequency Treatment

CPAP-RFP
Start date: November 2014
Phase: N/A
Study type: Interventional

The project aims to study whether the application of a continuous positive airway pressure (CPAP) of 4 cm water vapor is a safe method in pulmonary radiofrequency intervention (PRF) lung cancer under conscious sedation compared with placebo. And, assess whether CPAP prevents atelectasis formation and consequently reduces the potential complications of PRF and improves procedural success

NCT ID: NCT02055807 Completed - Atelectasis Clinical Trials

Role of Lung Ultrasound Imaging in the Comparison of Two Mechanical Ventilation Strategies During Laparotomy

Start date: February 2015
Phase: N/A
Study type: Interventional

The use of positive end-expiratory pressure (PEEP) and recruitment maneuvers during laparotomy will limit the development of atelectasis and therefore improve the aeration score.

NCT ID: NCT01993394 Completed - Atelectasis Clinical Trials

Effect of Hyperoxia and Hypergravity on Lung Ventilation and Perfusion

Start date: October 2011
Phase: N/A
Study type: Interventional

The primary aim of this project is to get further knowledge on the effects of + Gz accelerations and hyperoxia on lung ventilation in humans. The secondary aim is to study lung perfusion and cardiovascular function in these conditions.