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Astigmatism clinical trials

View clinical trials related to Astigmatism.

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NCT ID: NCT04698590 Active, not recruiting - Keratoconus Clinical Trials

Wavefront Guided Scleral Lenses for Keratoconus and Irregular Astigmatism

WFG Sclerals
Start date: January 15, 2021
Phase: N/A
Study type: Interventional

Aberrations are the spreading of light from a point focus. Aberrations of the eyes can be objectively evaluated with a wavefront aberrometer. Lower order aberrations such as defocus and astigmatism can be corrected with glasses and traditional/disposable soft contact lenses. Patients with ectatic corneal disease, such as keratoconus, or irregular astigmatism cause by surgery, trauma or disease, experience vision that is unlikely to be adequately corrected with glasses or disposable soft contact lenses due to higher order aberrations (HOA). HOA's cause halos, flare, glare, starbursts, doubling, smearing or ghosting of vision. Specialty contact lenses, such as scleral lenses, can be used to mask the irregularity of the cornea, reducing HOA's and improving vision. In many patients the resultant vision, though improved, still has some level of residual HOA's affecting the quality of vision. Custom scleral lenses with customized wavefront guided optics can be used to reduce residual HOA's and improve vision further. These lenses have been referred to as higher order aberration correcting scleral lenses or HOA correcting sclerals and wavefront guided scleral lenses or WFG sclerals.

NCT ID: NCT04616144 Active, not recruiting - Hyperopia Clinical Trials

Fresh Corneal Lenticule Implantation in Hyperopic Patients With High Astigmatism

Start date: May 1, 2019
Phase: N/A
Study type: Interventional

The refractive combination of high hyperopia with high astigmatism is difficult to treat surgically. In addition, there are not many suitable options to offer such patients presenting with this condition. The method used at the EYE Hospital Pristina using fresh lenticule implantation by ReLex-SMILE is safe and effective method. Fresh Corneal Implantation is a safe treatment for hyperopia with high astigmatism comparing with refractive IOL implantation (loss of accommodation, endophthalmitis). Its primary objective is to increase visual acuity, accommodation process, patient satisfaction which makes patient to enjoy a happier life. We believe this study will be the future of refractive surgery for treating high hyperopia.

NCT ID: NCT04516772 Active, not recruiting - Myopic Astigmatism Clinical Trials

STAAR Visian Toric ICL Post-Approval Study

TICL-PAS
Start date: July 21, 2020
Phase: N/A
Study type: Interventional

The objective of this study is to evaluate the long term (i.e. 24 months) clinical performance of the Visian® Toric Implantable Collamer® Lens (ICL).

NCT ID: NCT03610997 Active, not recruiting - Hyperopia Clinical Trials

Photorefractive Keratectomy for Severe Anisometropia and Isoametropia Associated With Amblyopia

Start date: January 1, 2001
Phase: N/A
Study type: Interventional

Photorefractive keratectomy (PRK) with excimer laser has been used successfully to treat myopia, hyperopia, and astigmatism in adults for over 35 years. Children with high refractive errors that go untreated will develop severe amblyopia. PRK can normalize high refractive errors and potentially improve the visual acuity in affected children. The purpose of this study is to investigate whether children with high anisometropia or isoametropia with amblyopia that are nonresponsive to standard therapy and receive PRK develop better longterm visual acuity.

NCT ID: NCT03313921 Active, not recruiting - Myopia Clinical Trials

The MORE Study: Manifest vs. Online Refraction Evaluation

MORE
Start date: January 4, 2018
Phase: N/A
Study type: Interventional

The assessment of the refractive state of the eye is a fundamental and important part of ophthalmic and optometric clinical practice. The development of an unsupervised online subjective refraction method makes a refraction more accessible and can be quite cost-saving. In this study, the investigators want to validate an online refraction method which was recently created in the Netherlands. The study comprises two different set of participants: Part one contains fifty healthy volunteers, 18-40 years of age, with a refractive error and no other ophthalmic pathology. Part two contains fifty patients with an ophthalmic pathology. The online refraction outcomes will be compared to a manifest refraction and automated refraction in a cross-sectional study design.

NCT ID: NCT02565537 Active, not recruiting - Astigmatism Clinical Trials

High Resolution Wavefront-guided vs. Wavefront Optimized LASIK

Start date: October 2015
Phase: N/A
Study type: Interventional

The investigators are comparing outcomes of LASIK surgery using a high definition wavefront-guided laser to a wavefront-optimized laser in patients with nearsightedness with and without astigmatism.

NCT ID: NCT02328157 Active, not recruiting - Cataract Clinical Trials

Combined 25-gauge Vitrectomy and Cataract Surgery With Toric Intraocular Lens With Idiopathic Epiretinal Membrane.

Start date: January 2015
Phase: N/A
Study type: Interventional

Toric intraocular lens (IOL) is now widely used for the cataract surgery with preoperative corneal astigmatism. Symptomatic epiretinal membrane (ERM) is often treated with 25-gauge transconjunctival sutureless vitrectomy, resulting in good visual recovery. So far, however, limited information is available on the the stability of axis rotation, astigmatism correction, and improvement in uncorrected distance visual acuity, using astigmatism-correcting IOL in a 25-gauge transconjunctival sutureless vitrectomy combined with cataract surgery. In the current study, eyes with a preoperative corneal cylinder of more than 0.75 diopter had a triple procedure for idiopathic ERM using a toric IOL. Outcome measures will be the amount of IOL axis rotation, uncorrected visual acuity, corrected distance visual acuity, and corneal and refractive astigmatism up to 6 months postoperatively. We are expecting to show that postoperative IOL axis stability is similar to that reported for cataract surgery alone in vitrectomy (triple procedure) for idiopathic ERM with a toric IOL.

NCT ID: NCT01628146 Active, not recruiting - Clinical trials for Hyperopic Presbyopia

Prospective Investigation of SUPRACOR Visual Outcomes of Presbyopic Hyperopic Patients With and Without Astigmatism

Start date: September 2012
Phase: Phase 4
Study type: Interventional

This phase IV study is an open, prospective, single-center, single-surgeon bilateral eye study to investigate the bilateral uncorrected intermediate visual acuity of presbyopic hyperopic patients, who have been treated with Presbyopia Algorithm SUPRACOR.

NCT ID: NCT01404884 Active, not recruiting - Myopia Clinical Trials

SUPRACOR for Myopia and Myopic Astigmatism

SUPRACOR
Start date: June 2011
Phase: Phase 3
Study type: Interventional

This clinical study has been planned to evaluate the safety and effectiveness of the SUPRACR presbyopic excimer laser treatment algorithm for myopic eyes developed for applying to the cornea of the human eye in a single center. The developed software algorithm uses the subjective refraction of the eye to create a treatment for the distance vision correction. This part of the treatment does not show any difference to a regular aspheric LASIK treatment for myopic cases. In addition to the treatment for the distance vision an additional central ablation component will be added to address the near vision. The study design is applied as a single center unilateral eye safety and effectiveness study of the SUPRACOR presbyopic algorithm for myopia with a 3 months postoperative follow up.

NCT ID: NCT01058629 Active, not recruiting - Astigmatism Clinical Trials

Study to Evaluate the Clinical Performance of SynergEyes A2 Hybrid Contact Lenses

Start date: August 2009
Phase: N/A
Study type: Interventional

This is a multicenter study to evaluate the clinical performance of the SynergEyes A2 lens in patients with refractive errors with or without astigmatism.