Asthma Clinical Trial
— GLADOfficial title:
GPIAG and Leicester Asthma and Dysfunctional Breathing (GLAD) Study: a Randomised Controlled Study
Verified date | November 2015 |
Source | University of Aberdeen |
Contact | n/a |
Is FDA regulated | No |
Health authority | United Kingdom: Research Ethics Committee |
Study type | Interventional |
Breathing retraining supervised by a physiotherapist will result in improvements in the
quality of life and asthma control of patients treated for asthma in the community with
symptoms suggestive of dysfunctional breathing.
To investigate the effects of breathing retraining on clinical and physiological parameters
of asthma control, to identify the characteristics of patients who benefit, to perform a
health economic evaluation.
Status | Completed |
Enrollment | 182 |
Est. completion date | December 2007 |
Est. primary completion date | December 2007 |
Accepts healthy volunteers | No |
Gender | Both |
Age group | 17 Years to 70 Years |
Eligibility |
Inclusion Criteria: - Asthma diagnosis in medical records - Age 17-70 yrs. - One or more prescription for asthma medication in previous 12 months - Impaired asthma related quality of life (AQLQ score <5.5) Exclusion Criteria: - COPD - Unstable or under-treated asthma at enrollment. |
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Single Blind (Outcomes Assessor), Primary Purpose: Treatment
Country | Name | City | State |
---|---|---|---|
n/a |
Lead Sponsor | Collaborator |
---|---|
P Burns | University Hospitals, Leicester |
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Change in AQLQ scores between intervention and control groups in subjects with positive NQ screening scores 1 month post intervention Change in AQLQ scores between intervention groups of subjects with positive and negative NQ screening scores | Dec 2006 | ||
Secondary | Changes in bronchial hyperresponsiveness(PC 20), sputum eosinophil counts and exhaled NO between intervention and control groups in subjects with positive and negative NQ screening scores Change in ACQ Score between the intervention and the control gr | Dec 2007 |
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