Asthma Clinical Trial
Official title:
GPIAG and Leicester Asthma and Dysfunctional Breathing (GLAD) Study: a Randomised Controlled Study
Breathing retraining supervised by a physiotherapist will result in improvements in the
quality of life and asthma control of patients treated for asthma in the community with
symptoms suggestive of dysfunctional breathing.
To investigate the effects of breathing retraining on clinical and physiological parameters
of asthma control, to identify the characteristics of patients who benefit, to perform a
health economic evaluation.
Objectives:
- To assess the effect of breathing retraining on asthma-related health status, asthma
control and objective indices of asthma severity (bronchial hyper-reactivity (BHR),
sputum eosinophilia and nitric oxide production) in patients with symptomatic asthma.
- To compare the relationship between symptoms of dysfunctional breathing (Nijmegen
Questionnaire screening score), changes in asthma-related health status and other
parameters resulting from breathing retraining
- To explore the relationship between dysfunctional breathing, baseline asthma symptoms,
treatment and asthma-related quality of life.
- To estimate the cost effectiveness of the breathing retraining intervention
;
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Single Blind (Outcomes Assessor), Primary Purpose: Treatment
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