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Arthropathy clinical trials

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NCT ID: NCT06440863 Completed - Obesity Clinical Trials

Postoperative BMI Changes and Functional Outcomes in Knee and Hip Arthroplasty

Start date: January 1, 2018
Phase: N/A
Study type: Interventional

PURPOSE Obesity poses challenges to preoperative mobility and functional recovery for arthroplasty patients, yet postoperative weight loss remains elusive. This study aims to investigate postoperative weight changes and their impact on functional scores following knee and hip arthroplasty, exploring factors influencing these changes. METHODS A total of 459 knee and hip arthroplasty cases with a 2-year follow-up were analyzed. BMI and Oxford scores were tracked, alongside factors including comorbidities, corticosteroid use, physiotherapy, and unilateral vs. bilateral surgery. EXPECTED OUTCOMES Based on the study's design and the data available, we anticipate observing the impact of changes in patients' BMI on clinical scores as an independent variable. Additionally, we aim to elucidate the effects of comorbidities, corticosteroid use, physiatrist follow-up, and the type of surgical procedure on both BMI and clinical outcomes. Through this analysis, we expect to gain a comprehensive understanding of how these factors interplay to influence postoperative recovery and overall patient health.

NCT ID: NCT06053060 Completed - Arthropathy Clinical Trials

Evaluation of the Positioning of the Dynacup Cup "One C" Versus "Standard Dynacup"

DYNACUP
Start date: November 21, 2021
Phase: N/A
Study type: Interventional

The ceramic-ceramic friction pair is widely used today in total hip arthroplasty, including fourth-generation ceramics which show the lowest wear rate. These have considerably reduced the risk of head fracture compared to previous generations; however, the risk of insert rupture persists with rates similar to those of third generation ceramics. These ceramic fractures require complex revision surgery, which brings complications, exposing patients to the risk of third-body wear and tear related to persistent post-surgical debris. They are frequently due to an incorrect assembly of the ceramic causing intraoperative or early postoperative rupture. To fix this, manufacturers have developed pre-assembled cups in the factory. The Dynacup One C cup developed by Corin® corresponds to the pre-assembled version of the Dynacup cup, making it possible to eliminate the risk of anomaly during intraoperative assembly linked to the human factor and to offer patients with very small cups an adapted ceramic implant. A single study with a small sample compared the two implants (pre-assembled version [vs] modular version) clinically, radiologically and functionally without showing any significant difference. The lack of data in the literature comparing these two implants motivated us to conduct a randomized comparative study on a large sample of patients.

NCT ID: NCT06002139 Completed - Anxiety Clinical Trials

Virtual Reality in Orthopedic Rehabilitation

Start date: June 1, 2023
Phase: N/A
Study type: Interventional

The study's objective is to evaluate the efficacy of implemented Virtual Reality therapy for patients who have undergone lower limb arthroplasty and are in inpatient rehabilitation. The study aim to examine its influence on reducing anxiety levels, mitigating depressive symptoms, enhancing motivation for elderly patients to participate in physiotherapy, and improving their overall functional state and fall risk.

NCT ID: NCT05840705 Recruiting - Obesity, Morbid Clinical Trials

Approach Modification for Total Knee Arthroplasty in Morbidly Obese Patients

Start date: January 1, 2018
Phase: N/A
Study type: Interventional

The study provides a detailed description of a smaller incision with better visualization in total knee arthroplasty operations

NCT ID: NCT05629130 Recruiting - Hemophilia Clinical Trials

Embolization in Hereditary Coagulopathies

EHCO
Start date: January 16, 2023
Phase: N/A
Study type: Interventional

This is a longitudinal, prospective study, which will include 30 subjects with hereditary coagulopathies, with arthropathy, chronic synovitis resulting from hemarthrosis of the elbows, knees and/or ankles followed up at the Centro de Hemofilia HCFMUSP, after approval by the ethics and research committee. They will undergo imaging tests (X-rays and Magnetic Resonance of knee, elbow, or ankle), physical, pain, quality of life and functional assessments (Hemophilia Joint Health Score, Functional Independence Score in Hemophilia, Perimeter, Test Timed up and Go, 30 second sit and stand test, Haemophilia - Adult - Quality of Life questionnaire (HAEM-A-QoL), Knee Injury and Osteoarthritis Outcome Score, EQ-5D, numerical rating scale for pain and embolization procedure (superselective embolization of target arteries with spherical microparticles Embosphere 100-300 micrometers (Biosphere Medical, Roissy, France), until partial vascular stasis and decharacterization of pathological synovial enhancement. These evaluations will be performed at baseline, 1, 3, 6, 12, 24, 36, 48 and 60 months after the procedure.

NCT ID: NCT05602753 Recruiting - Smoking Cessation Clinical Trials

Smoking Cessation Study

Start date: February 18, 2021
Phase:
Study type: Observational

The primary outcome of this study is to determine the true incidence of smokers among patients undergoing joint replacement and secondly, what percent are able to quit smoking before surgery under a structured cessation program with carbon monoxide breath testing. The investigators hypothesize that self-reported smoking status is underreported and that routine carbon monoxide breath testing will improve abstinence rates at the time of surgery.

NCT ID: NCT05591859 Recruiting - Hip Osteoarthritis Clinical Trials

Restoration Anatomic Acetabular Shell Revision Study

RAS
Start date: March 2, 2024
Phase: N/A
Study type: Interventional

This study will be a non-randomized, ambidirectional (retrospective and prospective) study where all subjects will be followed prospectively. The study will evaluate the survivorship of the RAS acetabular component in a previously failed total hip arthroplasty (THA) in a consecutive series of subjects who meet the eligibility criteria.

NCT ID: NCT05459948 Recruiting - Knee Replacement Clinical Trials

The Medacta GMK SpheriKA Post-Marketing Surveillance Study

Start date: July 30, 2022
Phase:
Study type: Observational

This is a Post-Marketing Surveillance of GMK SpheriKA knee stem prosthesis.

NCT ID: NCT05319223 Recruiting - Arthropathy Clinical Trials

Patient Blood Management in Orthopedic Surgical Patients in Turkey

PABMOS
Start date: February 1, 2022
Phase:
Study type: Observational

Transfusion practice for surgical patients has changed from replacing surgically lost blood with allogeneic blood transfusions to implementing strategies that reduce transfusion requirements. Patient Blood Management (PBM), which is "the timely application of evidence-based medical and surgical concepts designed to maintain haemoglobin concentration, optimize hemostasis and minimize blood loss in an effort to improve patient outcome. There is mounting evidence that multimodal patient blood management (PBM) programmes can be effective at improving postoperative outcomes and reducing perioperative blood transfusions and costs The Turkish Society of Anaesthesiologists PBM Task Force has been working on this subject and studied transfusion practice throughout all through the peri-operative periods. Unfortunately we documented a high transfusion rate in major surgical patients in Turkey. One of the surgeries, that has high transfusion rate, was orthopaedic surgery. According to our recent data we planned to implement PBM in major orthopaedic surgical patients and evaluate the effects PBM in transfusion rate and patient outcomes. While some elements of PBM have a strong evidence base in hip or knee replacement, such as the use of tranexamic acid (TXA) the evidence for preoperative anaemia optimisation with iron is less robust. Implementing PBM all through the operative period gains more importance.

NCT ID: NCT05295004 Recruiting - Sleep Disturbance Clinical Trials

The Effect of Mindfulness Training Before Primary Total Joint Arthroplasty on Sleep Quality

Start date: March 15, 2022
Phase: N/A
Study type: Interventional

The primary purpose of this study is the determine whether a 15 minute Mindfulness Meditation (MM) administered at the preoperative appointment prior to primary unilateral total joint arthroplasty (TJA) results in any improvement in Pittsburg Sleep Quality Index (PSQI) score, a validated metric for sleep quality, at 2, 6 or 12 weeks post-operatively.