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Arthritis Knee clinical trials

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NCT ID: NCT05760534 Not yet recruiting - Arthritis Knee Clinical Trials

Ideal Dosage for Sedation of Obese Patients Undergoing Knee or Hip Arthroplasty Under Spinal Anesthesia

Start date: March 6, 2023
Phase: Phase 4
Study type: Interventional

This study aims to compare ideal body weight- and total body weight-based dosage for remimazolam sedation of obese patients undergoing knee or hip arthroplasty under spinal anesthesia.

NCT ID: NCT05696418 Completed - Clinical trials for Arthroplasty Complications

Anterior Knee Pain in Mobile Bearing Versus Fixed Bearing in TKA

Start date: January 15, 2021
Phase: N/A
Study type: Interventional

Osteoarthritis is the most common cause of chronic joint disease, and its incidence has increased due to the high average life expectancy, in addition to the high incidence of obesity. Total knee arthroplasty is currently an accepted treatment for severe degenerative conditions and there are various implant systems with special features depending on component geometry, degree of fit of the articular surfaces, and fixation techniques. A tibial component with mobile polyethylene has been developed as an alternative to fixed polyethylene because it has theoretical advantages in terms of increasing the range of motion, reducing wear conditions, and reducing the incidence of anterior knee pain when the articular surface of the patella is not resurfaced.

NCT ID: NCT05693818 Recruiting - Arthritis Knee Clinical Trials

Quantitative Assessment of Walking (Squawk) With the Canary canturioTM te (CTE) Tibial Extension

Start date: January 31, 2023
Phase:
Study type: Observational

The objective of this prospective study is to demonstrate accuracy of a limp detection model using a healthcare provider assessment as the non-reference standard.

NCT ID: NCT05691751 Completed - Blood Loss Clinical Trials

Blood Loss Assessment in the Limited Application of Tourniquet During Primary Unilateral TKA

Start date: January 1, 2021
Phase: N/A
Study type: Interventional

Tourniquet application in total knee arthroplasty has many benefits and might have a role in the incidence of peri-operative complications the aim of this research: is to look into the effectiveness of the limited application of tourniquet during primary unilateral total knee arthroplasty and compare the perioperative complications with the standard full-time application.

NCT ID: NCT05659329 Completed - Arthritis Knee Clinical Trials

Retrospective Simplex High Viscosity (HV) Bone Cement Study

Start date: April 25, 2016
Phase:
Study type: Observational

This study is a retrospective multicenter study to review the use of Simplex High Viscosity Bone Cement in Primary Total Knee Arthroplasty

NCT ID: NCT05476367 Not yet recruiting - Arthritis Knee Clinical Trials

Patients With Asymptomatic Hyperuricemia Have Stronger Local Inflammatory Response and Worse Outcome After Total Knee Arthroplasty

Start date: August 1, 2022
Phase:
Study type: Observational

We identify all patients who had undergone primary total knee arthroplsty(TKA) from April 1, 2015, to March 30, 2016. Patients are grouped by uric acid level. The knee society score(KSS score) and the hospital for special surgery knee score (HSS score) before the surgery and 6 years after the surgery will be collected. Also the clinical data will be collected.

NCT ID: NCT05462483 Completed - Arthritis Knee Clinical Trials

Heat Application to Quadriceps Effect on Pain After a Total Knee Arthroplasty

Start date: June 1, 2022
Phase: N/A
Study type: Interventional

The goal of this study is to explore an under-researched aspect of recovery. Typically, post-operative care after a knee arthroplasty consists of compression (stockings), medications, rest, ice, elevation, physical therapy, and wound care. All of these treatments perform their role well, however, medications such opiates run the risk of addiction. An additional method of pain management such as heat application to the surrounding musculature warrants exploration. The goal of this study is to reduce the amount of pain, and improve the quality of life in post-operative patients. Pain, stiffness, symptoms, quality of life and function of the knee will be evaluated utilizing patient-reported measures and range of motion. Patients will be assessed using the Knee Injury and Osteoarthritis Outcome survey (KOOS Jr), Visual Analogue Scale (VAS) and PROMIS. Patients will be given these surveys during their two and six week check-in with the surgeon. In addition to these patient-reported measures, the investigators will also be tracking range of motion (ROM) and opioid usage. The data will then be collected via the patient's electronic health record, or by the researcher directly. The treatment group will be given a written order to apply heat to the quadriceps at least three times per day for 10-15 minutes each. This can be done in four hour increments or when patients symptoms begin to worsen. The patient will receive a rice sock for heat application. The control group will not be withheld from heat application, but will not be instructed to do so. The control group will instead follow the current standard of care as advised by the physician.

NCT ID: NCT05406245 Recruiting - Arthritis Knee Clinical Trials

The Effect of Stress on the Residual Gastric Volume

Start date: July 1, 2022
Phase:
Study type: Observational

In our institution, many patients undergo staged bilateral total knee arthroplasty at weekly intervals, and most of the patients are older adults with degenerative arthritis. As recommended, the older adult patients who undergoing total knee arthroplasty drink carbohydrate-containing fluid (400 ml) 2 hours prior to surgery. In this type of surgery, there are additional points to consider when applying the fasting guidelines. This is because, in addition to the factor of advanced age, which can affect gastric emptying time, the patient's physical, medical, and psychological conditions at the first and the second operation may be different. For example, the effect of the acute pain that occurs after the first total knee arthroplasty and subsequent opioids administered on gastric motility cannot be ignored. However, to date, there have been no studies examining the association of stress (emotional and surgical) and residual gastric volume of older adult patients with staged bilateral total knee arthroplasty and whether there is a difference according to the stage when carbohydrate-containing fluid is ingested. In the present study, the investigators will evaluate the effect of emotional stress, surgical stress, pain, and the use of opioids on the residual gastric volume in older adults undergoing staged-bilateral total knee arthroplasty.

NCT ID: NCT05290818 Not yet recruiting - Clinical trials for Osteo Arthritis Knee

Total Versus Robotic Assisted Unicompartmental Knee Replacement

TRAKER
Start date: September 2022
Phase: N/A
Study type: Interventional

The purpose of this research is to compare the functional outcomes of patients with end stage medial compartment OA of the knee undergoing a conventional mTKA to those undergoing rUKA and to assess the associated cost economics of such technology.

NCT ID: NCT05065775 Completed - Anesthesia Clinical Trials

Bioavailability of Intranasal Dexmedetomidine

INDEX
Start date: November 1, 2021
Phase: Phase 4
Study type: Interventional

Aim of this study is to characterize the pharmacokinetics of dexmedetomidine in supine, anesthetized adult patients after intranasal dosing.