Effect of Interval Training on Arterial Stiffness in Women With Hypertension

Arterial Stiffness Clinical Trial

Official title:

Effect of Interval Training on Arterial Stiffness in Women With Hypertension

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT04862754
• Other study ID #: P.T REC/012/003094.
• Status: Completed
• Phase: N/A
• Start date: January 25, 2021
• Est. completion date: April 15, 2021

Study information

• Verified date: March 2022
• Source: Cairo University
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

this study is aiming to assess the chronic effect of the interval training program on arterial stiffness in women with hypertension

Recruitment information / eligibility

• Status: Completed
• Enrollment: 50
• Est. completion date: April 15, 2021
• Est. primary completion date: March 30, 2021
• Accepts healthy volunteers: No
• Gender: Female
• Age group: 40 Years to 60 Years

Eligibility

Inclusion Criteria:

• physically inactive

• BMI 30-40

• Stage 1 and 2 hypertension

• Elevated BP as systolic BP =130 mm Hg and/or diastolic BP =85 mm Hg measured at the brachial artery.

Exclusion Criteria:

• Medications known to affect weight or appetite

• Any disease associated with exercise intolerance.

• Women were taking hormone replacement therapy

Related Conditions & MeSH terms

• Arterial Stiffness
• Hypertension

Intervention

Other:
• interval training exercise
interval training exercise

Locations

Country	Name	City	State
Egypt	Faculty of physical therapy	Cairo

Sponsors (1)

Lead Sponsor	Collaborator
Cairo University

Country where clinical trial is conducted

Egypt, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Central arterial stiffness measurements (Pulse Wave Velocity [PWV], augmentation index )	Pulse wave analysis (PWA) of the women in the two groups: pre and post treatment for pulse wave velocity (PWV) and augmentation index(AIx); Pulse Wave Velocity [PWV], augmentation index (AIx @75HR) and resting heart rate were measured using analysis equipment which called Non-invasive blood pressure measurement system using "Mobil-O-Graph 24h PWA " with Hypertension Management Software Client Server (HMS-CS 4.3). PWA was performed using an oscillometric Mobil-O-Graph R 24 h PWA Monitor device (I.E.M GmbH, Germany) with integrated ARCSolver® software	two months
Secondary	blood lipid profile	blood analysis will be used to measure lipid profile (high and low-density lipoprotein, cholesterol, triglyceride)	two months
Secondary	interleukin 6	blood analysis will be used to measure interleukin 6	two months
Secondary	blood pressure (systolic and diastolic)	resting Blood pressure was monitored from the right arm using an automated digital electronic BP monitor (Omron digital BP monitor, Model 11 EM 403c; Tokyo Japan).	two months