Lung Sonography in Patients With Acute Respiratory Distress Syndrome in Intensive Care Unit

ARDS Clinical Trial

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT01881061
• Other study ID #: UOA-US-2010
• Status: Completed
• Phase: N/A
• First received: June 17, 2013
• Last updated: June 18, 2013
• Start date: September 2009
• Est. completion date: December 2011

Study information

• Verified date: June 2013
• Source: University of Athens
• Contact: n/a
• Is FDA regulated: No
• Health authority: Greece: Ethics Committee
• Study type: Observational

Clinical Trial Summary

The purpose of this study is to evaluate the role of lung sonography during different PEEP settings in ICU patients with ARDS.

Description:

Acute respiratory distress syndrome (ARDS) is a clinical syndrome that often occurs in critically ill patients.

Patients with ARDS invariably require mechanical ventilation to improve oxygen transport. An improvement in oxygenation can be obtained by an increase in positive end-expiratory pressure (PEEP).

In critically ill patients with ARDS, lung imaging is been held by the use of chest radiography and the "gold standard" technique, Computed Tomography (CT).

We designed an observational study in which we included patients under mechanical ventilation admitted in our ICU. In all patients PEEP changes were applied and lung sonography was performed.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 10
• Est. completion date: December 2011
• Est. primary completion date: December 2011
• Accepts healthy volunteers: No
• Gender: Both
• Age group: 18 Years to 90 Years

Eligibility

Inclusion Criteria:

• Critically ill patients with ARDS admitted in ICU of Evangelismos Hospital

• length of stay > 48 hours

Exclusion Criteria:

• age < 18 years

• emphysema fractures or skin lesions that do not allow the implementation of lung sonography

• BMI > 35 kg/m2

• length of stay < 48 hours

Study Design

Observational Model: Case Control, Time Perspective: Prospective

Related Conditions & MeSH terms

• Acute Lung Injury
• ARDS
• Respiratory Distress Syndrome, Adult
• Respiratory Distress Syndrome, Newborn

Locations

Country	Name	City	State
Greece	First Critical Care Unit, Evaggelismos Hospital, School of Medicine, University of Athens	Athens	Attiki

Sponsors (1)

Lead Sponsor	Collaborator
University of Athens

Country where clinical trial is conducted

Greece, 

References & Publications (1)

Stefanidis K, Dimopoulos S, Tripodaki ES, Vitzilaios K, Politis P, Piperopoulos P, Nanas S. Lung sonography and recruitment in patients with early acute respiratory distress syndrome: a pilot study. Crit Care. 2011 Aug 4;15(4):R185. doi: 10.1186/cc10338. — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Non aerated lung area changes		20 min after PEEP trial	No
Secondary	Arterial oxygen and carbon dioxide partial pressure		20 min after PEEP trial	No