Clinical Trials Logo

Aortic Dissection clinical trials

View clinical trials related to Aortic Dissection.

Filter by:

NCT ID: NCT03233087 Recruiting - Aortic Aneurysm Clinical Trials

Diagnosis and Prognosis for Aortic Aneurysm aNd Dissection in Anzhen(DPANDA) Study

Start date: March 1, 2014
Phase:
Study type: Observational

The registry study aims to determine serial biomarkers to diagnosis and prognosis of aortic aneurysm/aortic dissection.

NCT ID: NCT02837120 Recruiting - Clinical trials for Acute Myocardial Infarction

Retrospective Study of Acute Chest Pain in Extremely Critical Condition for More Than Ten Years

RESPECT
Start date: June 2016
Phase: N/A
Study type: Observational

Acute non-traumatic chest pain is a common kind of symptom in extremely critical condition, with various pathogenesis and different level of risk . Chest pain in high risk takes 1/3 of that. It mainly includes acute coronary syndrome (including myocardial infarction and unstable angina pectoris, accounted for over 95% of chest pain in high risk), aortic dissection, pulmonary embolism etc, and is in high lethality and deformity. The investigators do the research : 1. To study the diagnosis and management condition of acute chest pain in extremely critical condition for last ten or more years in Qilu Hospital,Shandong University. 2. To discuss the significance of key accompanying symptoms(for example radiating pain, chest distress, sweating, nausea etc), physical signs and lab examination in early diagnosis and risk stratification of acute chest pain in extremely critical condition. 3. To study the effect factors of thrombus burden in STEMI patients, at the same time, creat a a simple, practical and scientific method of blood clots classification.

NCT ID: NCT02816892 Recruiting - Aortic Dissection Clinical Trials

Significance of Serum Tenascin C in Patients With Acute Aortic Disease

Start date: June 2016
Phase: N/A
Study type: Observational

This study aims to investigate Serum Tenascin C levels in patients with acute symptoms relating to a known or newly diagnosed aortic aneurysm in emergency department and reveals the possible role of Tenascin C in the development of the disease.

NCT ID: NCT02630212 Recruiting - Aortic Dissection Clinical Trials

The Relationship Between ALDH2 and Aortic Dissection

RALAD
Start date: December 2015
Phase:
Study type: Observational

The purpose of this study is to evaluate the impact of ALDH2 Glu504Lys polymorphism on aortic dissection.

NCT ID: NCT02323581 Recruiting - Clinical trials for Aortic Aneurysm, Thoracic

Endovascular Treatment of TAAA and Aortic Arch Aneurysms Using Fenestrated and Branched Stent Grafts

Start date: November 2013
Phase: N/A
Study type: Interventional

Prospective, nonrandomized, single-center, two-arm study to assess the feasibility and safety and to evaluate clinical outcomes of endovascular repair of complex aortic aneurysms (thoracoabdominal aortic aneurysms and aortic arch aneurysms) in patients at high risk for open surgery.

NCT ID: NCT02306200 Recruiting - Heart Failure Clinical Trials

Cardiovascular Health Improvement Project

CHIP
Start date: August 2013
Phase:
Study type: Observational [Patient Registry]

The goal of this project is to establish a biobank of clinical information, DNA, plasma, and aortic tissue samples from patients with cardiovascular disease as well as healthy controls.

NCT ID: NCT02201589 Recruiting - Aortic Dissection Clinical Trials

Feasibility of Endovascular Repair Of Ascending Aortic Pathologies

Start date: September 2013
Phase: N/A
Study type: Interventional

The purpose of this study is to investigate the outcome of patients with pathologies of the ascending thoracic aorta (diseases in the great blood vessel or artery that leads away from the heart) including type A aortic dissection, retrograde type A aortic dissection, intramural hematoma, penetrating ulcer or pseudoaneurysm who are suitable for endovascular (within the vessel) repair with the Medtronic Valiant PS-IDE (Physician Sponsored-Investigational Device Exemption) Stent Graft. Type A aortic dissection is a condition where blood passes through the inner lining or between the layers of the blood vessel from a tear in the aortic wall (dissection) in the ascending aorta; a retrograde Type A aortic dissection is a condition where the dissection or tear in the ascending aorta starts from the descending aorta; an intramural hematoma is a collection of clotted blood within the aortic wall; a penetrating ulcer has a plaque or clot within the wall and a pseudoaneurysm is a false aneurysm . If left untreated in any of these conditions, the aorta can enlarge and rupture causing injury or death. The plan for these patients is to repair the ascending thoracic aorta using the Medtronic Valiant PS-IDE Stent Graft with the Captivia Delivery System. The Valiant Captivia has been evaluated worldwide and used extensively in patients with type B (descending) thoracic aortic dissection. Since the dissections in the ascending aortas mirror that of the descending aorta, it is expected that this stent graft will deliver similar performance and endurance in patients with type A aortic dissection. The investigators expect to reroute the blood to the true lumen (the inner space within the blood vessel) by covering the proximal (nearest to the heart) tear with the stent graft. The stent graft is a stent frame made from Nitinol wire and covered with an expandable material made of a polyester material. This new study will determine how well the device works to treat dissections, intramural hematomas, penetrating ulcers and pseudoaneurysms in the ascending thoracic aorta.

NCT ID: NCT01967511 Recruiting - Clinical trials for Spontaneous Coronary Artery Dissection

Defining the Basis of Fibromuscular Dysplasia (FMD)

DEFINE
Start date: October 2013
Phase:
Study type: Observational

The purpose of this study has evolved and expanded since its inception. Originally the intent was to establish the functional, molecular and genetic profile of fibroblasts from Fibromuscular Dysplasia (FMD) patients as compared to carefully matched control subjects. While this remains among the objectives, the study has been expanded to undertake a fully powered cross-tissue systems genetics analysis of FMD, and now also the related arteriopathies spontaneous coronary artery dissection (SCAD) and cervical artery dissection (CvAD). The overall objective is to disclose the core biologic mechanisms of these disorders.

NCT ID: NCT01552720 Recruiting - Aortic Dissection Clinical Trials

Clinical Characteristics, Management and Outcomes of Chinese Patients With Acute Aortic Dissection

CCMOCPAAD
Start date: January 2011
Phase: N/A
Study type: Observational

Data reported by the international registry of acute aortic dissection (IRAD) in not sufficient to reflect clinical characteristics of acute aortic dissection in China. Moreover, clinical characteristics of Acute aortic dissection have not evaluated to data. The aim of this study is analyze changing trend of clinical characteristics of Chinese patients with acute aortic dissection.

NCT ID: NCT01429727 Recruiting - Clinical trials for Spontaneous Coronary Artery Dissection

The "Virtual" Multicenter Spontaneous Coronary Artery Dissection (SCAD) Registry

SCAD
Start date: July 2011
Phase:
Study type: Observational

The primary goal of this project is to describe the clinical and physiologic characteristics of Spontaneous Coronary Artery Dissections (SCAD) in order to increase awareness, understanding, treatment and prevention of a potentially fatal cardiovascular event. This study will be a retrospective and prospective review of medical course and current health of men and women with SCAD.