The Effect of Different Muscle Training on Activities of Daily Living in COPD

Anxiety Clinical Trial

Official title:

Comparison of the Effects of Quadriceps and Gastrocnemius Muscle Training on Activities of Daily Living in COPD

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT05501457
• Other study ID #: HititUApayas
• Status: Recruiting
• Phase: N/A
• Start date: July 15, 2022
• Est. completion date: November 1, 2022

Study information

• Verified date: August 2022
• Source: Hitit University
• Contact: Ahmet Payas, Dr
• Phone: 05343483399
• Email: ahmetpayas[@]hitit.edu.tr
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Chronic obstructive pulmonary disease (COPD) contributes significantly to global morbidity and mortality; It is a disease that affects an estimated 210 million people worldwide and is the third most common cause of death. COPD is identified by persistent airflow limitation and is associated with progressively worsening lung function, dyspnea, health-related quality of life (HRQOL), and impaired exercise capacity. Poor exercise capacity is a common finding of chronic obstructive pulmonary disease (COPD). Central cardiopulmonary factors, respiratory muscle dysfunction, gas exchange abnormalities, and skeletal muscle dysfunction all play a role in limiting exercise capacity The aim of this study is to investigate the effects of neuromuscular electrical stimulation applied to different muscle groups (quadriceps femoris and gastrocnemius muscles) on exercise performance and quality of life in patients with stable COPD and compare it with standard treatment.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 45
• Est. completion date: November 1, 2022
• Est. primary completion date: October 1, 2022
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 18 Years to 75 Years

Eligibility

Inclusion Criteria:

• Being between 18-75 years old,
• Diagnosed as group B stable COPD according to GOLD criteria by a pulmonologist,
• PaO2 >55 mm Hg, PaCO2 <45 mmHg in room air.

Exclusion Criteria:

• Exacerbation,
• Cor pulmonale or respiratory muscle fatigue (abdominal paradoxical breathing),
• Cardiac instability (with acute MI, congestive heart failure, or uncontrollable arrhythmia),
• Musculoskeletal disorder (conditions affecting exercise ability),
• Difficulty communicating.

Related Conditions & MeSH terms

• Anxiety
• Quality of Life

Intervention

Device:
• Muscle strengthening with neuromuscular electrical stimulation
The effect of peripheral muscle strengthening training in addition to pulmonary rehabilitation in COPD patients on the patient's performance will be examined.

Locations

Country	Name	City	State
Turkey	Hititi University Sungurlu Vocational School	Corum

Sponsors (1)

Lead Sponsor	Collaborator
Hitit University

Country where clinical trial is conducted

Turkey, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	6 Minute Walk Test (6 MWT):	they could walk for 6 minutes, according to heart rate, blood pressure, respiratory rate, finger oxygen saturation, the walking distance at the end of walking, and dyspnea score according to the Modified Borg Scale (MBS) at the beginning and end of walking was recorded. Change from baseline 6 Minute walking performance after 4 weeks will be examined.	4 weeks
Secondary	Modified Borg Scale (MBS):	It consists of 10 items that define the severity of dyspnea according to their degrees. Change from baseline dyspnea after 4 weeks will be examined.	4 weeks
Secondary	St. George's Respiratory Questionnaire (SGRQ):	This questionnaire was developed specifically to determine the severity of the disease in COPD and asthma. Change from baseline severity of the disease after 4 weeks will be examined.	4 weeks
Secondary	Beck Depression Inventory (BDI):	It measures the behavioral findings of depression in adolescents and adults. Change from baseline depression status after 4 weeks will be examined.	4 weeks