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Anosmia and / or Ageusia and Early Corticosteroid Use

Covid19 Clinical Trial

Official title:
Anosmia and / or Ageusia in COVID-19: Timeline, Treatment With Early Corticosteroid and Recovery

Clinical Trial Summary

Time to recover of Anosmia and / or ageusia and early corticosteroid use

Clinical Trial Description

In a study of dexamethasone kinetics in two groups of 15 patients with community-acquired pneumonia, one group was treated with dexamethasone 6 mg/day by mouth and the other with 4 mg/day intravenously. The apparent volume of distribution was 1 L/kg in both groups, but the half-life after oral administration was approximately 7 hours, and after intravenous administration 9 hours. The bioavailability of oral dexamethasone was 81% (95% CI = 54-121%). However, the biological half-life of dexamethasone is much longer, of the order of 36-54 h compared with 18-36 h for prednisolone. Time to recover of Anosmia and / or ageusia and early corticosteroid use ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04528329
Study type Interventional
Source ClinAmygate
Contact Emad R Issak, MD
Phone 01272228989
Email dr.emad.r.h.issak@gmail.com
Status Recruiting
Phase Phase 4
Start date March 30, 2021
Completion date December 30, 2023
View Details
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