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The Effect of Aspirin on Angiogenesis Proteins in Women on Tamoxifen Therapy

Breast Cancer Clinical Trial

Official title:
The Impact of the Anti-Platelet Agent Aspirin on Angiogenesis Proteins in Women With Breast Cancer

Clinical Trial Summary

Changes in major angiogenic proteins have been seen following initiation of tamoxifen and aromatase inhibitor therapy in women with breast cancer. One source of these proteins is the circulating platelet pool. The investigators hypothesize that in addition to their anti-platelet properties, agents such as aspirin can be used as targeted anti-angiogenesis therapy. The investigators will determine the influence of aspirin on the release of angiogenic proteins from platelets in 35 patients with breast cancer.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT00727948
Study type Interventional
Source University of Vermont
Contact
Status Completed
Phase Early Phase 1
Start date July 2008
Completion date December 2012
View Details
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