Clinical Trials Logo
  1. Home
  2. Angina, Stable
  3. NCT01550614

Efficacy and Safety of Ad5FGF-4 for Myocardial Ischemia in Patients With Stable Angina Due to Coronary Artery Disease — ASPIRE  

Angina, Stable Clinical Trial

Official title:
A Randomized, Controlled, Parallel Group, Multicenter Phase 3 Study to Evaluate the Efficacy and Safety of Ad5FGF-4 Using SPECT Myocardial Perfusion Imaging in Patients With Stable Angina Pectoris

Clinical Trial Summary

The purpose of this study is to determine whether a single intracoronary infusion of Ad5FGF-4, delivered during induced transient ischemia, is effective in improving myocardial perfusion, angina functional class, patient symptoms, and quality of life. Short-term (8 weeks) and long-term (12 month) safety of Ad5FGF-4 will also be evaluated. The primary endpoint is change in adenosine triphosphate (ATP) stress SPECT reperfusion defect size.

Clinical Trial Description

n/a

Study Design

Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT01550614
Study type Interventional
Source Cardium Therapeutics
Contact
Status Terminated
Phase Phase 3
Start date March 2012
View Details
See also
  Status Clinical Trial Phase
Recruiting NCT05562037 - Stepped Care vs Center-based Cardiopulmonary Rehabilitation for Older Frail Adults Living in Rural MA N/A
Recruiting NCT02870764 - The Effect of Dan-shen Extract On Lipoprotein Associated PHospholipase A2 Levels IN Patients With Stable Angina Pectoris Phase 4
Completed NCT04648306 - Restore EF Observational Study
Recruiting NCT05933083 - MCNAIR Study: coMparative effeCtiveness of iN-person and teleheAlth cardIac Rehabilitation N/A
Not yet recruiting NCT02280850 - Efficacy and Safety Study of Guanxin Shutong Capsule to Treat Chronic Stable Angina Phase 4
Completed NCT04785846 - Registry of RESOLUTE-ONYX™ Zotarolimus-eluting Stent Utilization in Percutaneous Small Vessel Coronary Interventionism.
Completed NCT03759067 - Method of Clopidogrel Pre-treatment Undergoing Conventional Coronary Angiogram in Angina Patients N/A
Not yet recruiting NCT03306550 - Mechanism of Drug-drug Interaction Between Salvianolate Injection and Aspirin N/A
Completed NCT03193294 - CORonary MICrovascular Angina (CorMicA) N/A
Completed NCT04131816 - HeartHome: A Nurse-Driven, Home-Based Cardiac Rehabilitation Program N/A
Recruiting NCT06075602 - COMPLEX Registry - A Prospective COhort Study to Describe the Management and Outcomes of Patients Presenting With compLEX and Calcified Coronary Artery Disease
Recruiting NCT03783351 - Genotyping GUided Antiplatelet theRapy in pAtieNts Treated With Drug Eluting stEnts (GUARANTEE) N/A
Not yet recruiting NCT05857904 - Clinical Outcomes of CT-FFR Versus QFR-guided Strategy for Decision-Making in Patients With Stable Chest Pain N/A
Recruiting NCT01838148 - Biochemical and Electrocardiographic Signatures in the Detection of Exercise-induced Myocardial Ischemia
Terminated NCT02914834 - Acupuncture for Individuals With Stable Angina N/A
Not yet recruiting NCT06325020 - Objective Risk Assessment in Patients With Possible Anginal Chest Pain Using Leading Technology
Recruiting NCT05825339 - Absolute Flow for Ischemia With No Obstructive Coronary Arteries
Completed NCT05804500 - RecoveryPlus Telerehab Platform Pilot Study N/A
Completed NCT03518645 - Optimal Lesion Preparation With Non-compliant Balloons Before Implantation Of Bioresorbable Scaffolds N/A
Recruiting NCT05056662 - Post-Revascularization Optimization and PHysiological Evaluation of intermediaTe Lesions