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Aneurysm clinical trials

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NCT ID: NCT04502147 Completed - Clinical trials for Arterial Splenic Aneurysm

How to Provide Vascular Control of Splenic Artery Aneurysm? Report of Two Cases

Start date: July 1, 2020
Phase:
Study type: Observational

Spleen artery aneurysm represents the most common visceral aneurysm and the third most common splanchnic aneurysm. Most patients have no symptoms and are diagnosed as a part of other diagnostic focuses and examinations. The investigators present two patients with splenic artery aneurysms localized in the splenic hilum, who auspiciously undergo laparoscopic splenectomies with hem-o-lock clips in the vascular hilum without complications. These two cases showed that in addition to the numerous advantages of minimally invasive approaches, there is the possibility to improve laparoscopic technique in terms of safety and economic reasons by using hem - o - lock clips as a hemostatic technique securing the vascular elements of the splenic hilum.

NCT ID: NCT04489277 Completed - Clinical trials for Aortic Arch Aneurysm

Silent Brain Infarction After Endovascular Arch Procedures

Start date: September 1, 2018
Phase:
Study type: Observational [Patient Registry]

This is the largest study to evaluate incidence and distribution of silent cerebral infarction (SBI) following endovascular repair for disease of the aortic arch. Also, it is the first cohort to include total endovascular arch repair and devices flushed with carbon dioxide (CO2) to prevent gaseous cerebral embolization.

NCT ID: NCT04439760 Completed - Brain Aneurysm Clinical Trials

Superior Cervical Ganglion Block, Transcranial Doppler

Start date: October 1, 2020
Phase: N/A
Study type: Interventional

The aim of this study is to assess blood flow velocity in middle cerebral artery measured by transcranial doppler to determine the efficacy of SCG block in decreasing incidence or severity of vasospasm after MCA aneurysm surgery.

NCT ID: NCT04430114 Completed - Aneurysm Abdominal Clinical Trials

MuLtibranchEd Graft for OPen RepAir of ThoRacoabdominal Aneurysms

Start date: June 5, 2020
Phase: N/A
Study type: Interventional

The objective of the study is the evaluation of the technical success and clinical outcomes of the surgical treatment of thoraco-abdominal aortic aneurysms treated by Jotec "TAAA spinal loop graft" "custom made "CE equivalent" branched prosthesis, compared with the patient cohort already treated with standard and / or bench-top prostheses Gelweave ™ Coselli Thoracoabdominal Grafts.

NCT ID: NCT04409717 Completed - Clinical trials for Abdominal Aortic Aneurysm

Evaluation of the Long Term Efficacy of Endovascular Treatment of Type 2 Endoleaks

Start date: January 1, 2020
Phase:
Study type: Observational

Endovascular treatment has become the first choice to repair abdominal aortic aneurym, but exposes patients to a risk of endoleaks. Although treatment of type 1 and 3 endoleaks has proven to prevent aneurysms from rupture, controversies remain about type 2 endoleaks. The investigators described the different techniques of type 2 endovascular repair, and their efficacy at short and long term..

NCT ID: NCT04333641 Completed - Clinical trials for Abdominal Aortic Aneurysm (AAA)

Development of Novel Imaging Markers Predicting the Progression of Abdominal Aortic Aneurysm Using 3D Computed Tomography

Start date: April 3, 2020
Phase:
Study type: Observational

Study purpose: This study will investigate anatomical factors associated with increased risk of major adverse aorta-related event and accelerated growth of abdominal aneurysm based on 3-dimensional analysis of CT images. Study design: a multicenter single-arm prospective observational study. Subject: patients with small abdominal aortic aneurysm with maximal diameter of 30-50 mm (n=323) Methods: Patients diagnosed with small AAA based on CT will be enrolled after considering inclusion and exclusion criteria and prospectively followed clinically and with CT at 1 year. Primary endpoint: Major adverse aorta-related events (death, aortic rupture, or aneurysm growth >0.4 cm per year) at 1 year Secondary endpoints: 1) clinical events : death, aortic rupture, aneurysm growth >0.4 cm per year, surgical or endovascular repair 2) Changes in CT parameters of aneurysm: diameter, volume, wall shear stress

NCT ID: NCT04325373 Completed - Clinical trials for Abdominal Aortic Aneurysm

Abdominal Aortic Aneurysm Surgery and Thrombosis

AAA-IT
Start date: November 21, 2019
Phase:
Study type: Observational

The aim of our study is to evaluate the incidence of post-operative thrombotic complications after abdominal aortic aneurysm surgery in the context of atherosclerosis or infectious aneurysm and its links with preoperative inflammation and hemostasis.

NCT ID: NCT04315168 Completed - Clinical trials for Intracranial Aneurysm

FRED and FRED JR Devices for Intracranial Aneurysm Treatment

Start date: June 12, 2020
Phase:
Study type: Observational [Patient Registry]

A French, multicenter, prospective, observational, "real-world" assessment of the safety and efficacy of FRED and FRED Jr devices in the treatment of intracranial aneurysms

NCT ID: NCT04269408 Completed - Clinical trials for Aneurysmal Subarachnoid Hemorrhage

A Safety and Efficacy Study of NicaPlant® in Aneurysmal Subarachnoid Haemorrhage Patients Undergoing Aneurysm Clipping

Start date: April 5, 2020
Phase: Phase 2
Study type: Interventional

This study of NicaPlant® is conducted in patients who have a subarachnoid haemorrhage. Patients will be randomized in two treatment groups. Both groups will receive the standard of care and the investigational group will receive in addition NicaPlant®. NicaPlant® is tested to reduce the long-term complications of aneurysmal subarachnoid haemorrhage (aSAH).

NCT ID: NCT04246125 Completed - Lung Neoplasms Clinical Trials

Patient Skin Dose in Interventional Radiology

DPPRI
Start date: October 13, 2020
Phase:
Study type: Observational

Studies on radiation induced patients' skin lesions in interventional radiology highlighted the need for optimized and personalized patient dosimetry and adapted patient follow-up. Measurements using Gafchromic® films or thermoluminescent dosimeters have long been the only way to accurately evaluate the maximum absorbed dose to the patient skin. However as these dose measurements are tedious and expensive, they could not be systematically applicable in clinical practice. Therefore, more practical calculation methods have been developed. These software programs calculate the skin dose using dosimetric information from images DICOM header or radiation dose structured reports (RDSRs). Validation studies of these software programs are rare and when existent have many limitations. Radiation Dose Monitor (RDM from Medsquare) is a software program for archiving and monitoring of radiation dose (DACS, Dosimetry Archiving Communication System) used in routine in the investigator's hospitals. A new functionality developed in RDM allows quick estimation without in-vivo measurements of the absorbed dose to the skin of the patient. Comparing RDM calculations with in-vivo measurements will enable this software validation so that it can be used in clinical routine. Main objective: to validate RDM software for calculating patient skin dose in interventional radiology.