Comparison of Erector Spinae Block and Combined Deep and Superficial Serratus Anterior Plane Block

Anesthesia Clinical Trial

Official title:

Comparision of the Effects of Ultrasound-guided Erector Spinae Block and Combined Deep and Superficial Serratus Anterior Plane Block on Perioperative Analgesia for Video-assisted Thoracoscopic Surgery.

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT06073197
• Other study ID #: 2020-11/19
• Status: Completed
• Phase: N/A
• Start date: July 2, 2020
• Est. completion date: February 25, 2021

Study information

• Verified date: October 2023
• Source: Uludag University
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Objective: The authors hypothesized that combined deep and superficial serratus anterior plane block (SAPB) is as effective as erector spinae plane block (ESPB) for intraoperative and postoperative analgesia for video-assisted thoracoscopic surgery.

Design: A prospective randomized controlled study. Participants: Adult patients undergoing elective video-assisted thoracoscopic surgery.

Interventions: Preoperative SAPB or ESPB implementation.

Description:

Plane blocks implemented on preoperative course on 35 patients for each group. Postoperative Visual Analogue Scale (VAS) scores (0-10), intraoperative and postoperative analgesic consumption was measured using Mann-Whitney test. In the postoperative phase, opioid side effects, complications related to plane blocks, mobilization time and length of hospital stay was recorded and measured.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 70
• Est. completion date: February 25, 2021
• Est. primary completion date: February 25, 2021
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years to 80 Years

Eligibility

Inclusion Criteria:

• American Society of Anaesthesiologists (ASA) classification I-II scheduled for elective VATS

Exclusion Criteria:

• Patients who did not give consent

• Local anaesthetic allergy

• Known or suspected coagulopathy

• Infection at the injection site

• History of thoracic surgery

• Severe cardiovascular disease

• Hepatic or renal insufficiency (glomerular filtration rate <15 ml/min/1.73 m2)

• Severe neurological or psychiatric disorders

• Chronic opioid use

Related Conditions & MeSH terms

• Analgesia
• Anesthesia
• Pain, Postoperative
• Thoracic

Intervention

Procedure:
• erector spinae plane block
Erector spinae plane block was implemented on preoperative course on 35 patients. Intraoperative analgesic (Fentanyl) consumption was measured for intraoperative effects of the erector spinae plane block. Postoperative Visual Analogue Scale (VAS, from 0 to 10) scores and postoperative analgesic (Morphine) consumption was measured using Mann-Whitney test.
• combined deep and superficial serratus anterior plane block
Combined deep and superficial serratus anterior plane block was implemented on preoperative course on 35 patients. Intraoperative analgesic (Fentanyl) consumption was measured for intraoperative effects of the erector spinae plane block Postoperative Visual Analogue Scale (VAS, from 0 to 10) scores and postoperative analgesic (Morphine) consumption was measured using Mann-Whitney test.

Locations

Country	Name	City	State
Turkey	Bursa Uludag University	Bursa

Sponsors (1)

Lead Sponsor	Collaborator
Uludag University

Country where clinical trial is conducted

Turkey, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	postoperative analgesic effects	The primary outcome is compare the postoperative analgesic effects of SAPB and ESPB applied under USG guidance before surgery in patients scheduled for VATS using VAS (Visual Analogue Scale from 0 to 10).	first 48 hours
Primary	intraoperative analgesic effects	The primary outcome is compare the intraoperative analgesic effects of SAPB and ESPB applied under USG guidance before surgery in patients scheduled for VATS by measuring perioperative fentanyl consumption in both groups.	intraoperative phase
Secondary	side effects	The secondary aim was to compare the opioid side effects. Patients were informed about opioid side effects and asked whether side effects were present.	first 48 hours
Secondary	complications	The secondary aim was to compare the complications related to the applied block. Patients were examined and evaluated for any complications related to the block.	first 48 hours
Secondary	mobilization	The secondary aim was to compare the mobilization time	first 48 hours
Secondary	stay of hospital	length of stay in the recovery unit and hospital	first 4 days