Risk Factors and Impact of Anesthesia Techniques on Myocardial Infarction Following Transurethral Resection of the Prostate

Anesthesia Clinical Trial

Official title:

Risk Factors and Impact of Anesthesia Techniques on Myocardial Infarction Following Transurethral Resection of the Prostate: a Nationwide Database Case Control Study

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT04047329
• Other study ID #: 104-6697B
• Status: Completed
• Start date: January 1, 1998
• Est. completion date: March 22, 2016

Study information

• Verified date: September 2015
• Source: Chang Gung Memorial Hospital
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

This study examined the risk factors and the influence of the type of anesthetic used during transurethral resection of the prostate (TURP) on subsequent incidence of myocardial infarction (MI).

Description:

This study utilized a population-based, nationwide dataset to evaluate the risk factors of MI for patients with benign prostate hypertrophy (BPH) who received TURP. Besides, The study also compared the different effects of general anesthesia (GA) and neuraxial anesthesia (NA) on the incidence of MI within 6 and 12 months after TURP.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 115025
• Est. completion date: March 22, 2016
• Est. primary completion date: December 31, 2012
• Gender: All
• Age group: N/A and older

Eligibility

Inclusion Criteria:

• Patients receiving TURP surgery (1998-2012)

Exclusion Criteria:

• Patients without anesthesia records

• Patients receiving both general and neuraxial anesthesia

• Mortality within 12 months of TURP

Related Conditions & MeSH terms

• Anesthesia
• Infarction
• Myocardial Infarction
• Transurethral Resection of Prostate Syndrome

Intervention

Other:
• general anesthesia or neuraxial anesthesia

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
Chang Gung Memorial Hospital

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Postoperative myocardial infarction	Patients experienced myocardial infarction after transurethral resection of the prostate (TURP)	within 6 months after the first admission for TURP
Primary	Postoperative myocardial infarction	Patients experienced myocardial infarction after transurethral resection of the prostate (TURP)	within 12 months after the first admission for TURP
Primary	Patient's age (year-old) that developed post-TURP myocardial infarction	We analyze age distribution of patients with post-TURP myocardial infarction	within 6 months after the first admission for TURP
Primary	Patient's age (year-old) that developed post-TURP myocardial infarction	We analyze age distribution of patients with post-TURP myocardial infarction	within 12 months after the first admission for TURP
Primary	Number of patients with pre-operative diagnosed Diabetes Mellitus developing post-TURP myocardial infarction	We analyze pre-operative diagnosed Diabetes Mellitus rate in patients who had myocardial infarction after the surgery of TURP.	within 6 months after the first admission for TURP
Primary	Number of patients with pre-operative diagnosed Diabetes Mellitus developing post-TURP myocardial infarction	We analyze pre-operative diagnosed Diabetes Mellitus rate in patients who had myocardial infarction after the surgery of TURP.	within 12 months after the first admission for TURP
Primary	Number of patients with pre-operative diagnosed disorders of lipoid metabolism developing post-TURP myocardial infarction	We analyze pre-operative diagnosed disorders of lipoid metabolism rate in patients who had myocardial infarction after the surgery of TURP.	within 6 months after the first admission for TURP
Primary	Number of patients with pre-operative diagnosed disorders of lipoid metabolism developing post-TURP myocardial infarction	We analyze pre-operative diagnosed disorders of lipoid metabolism rate in patients who had myocardial infarction after the surgery of TURP.	within 12 months after the first admission for TURP
Primary	Number of patients with pre-operative diagnosed gout developing post-TURP myocardial infarction	We analyze pre-operative diagnosed gout rate in patients who had myocardial infarction after the surgery of TURP.	within 6 months after the first admission for TURP
Primary	Number of patients with pre-operative diagnosed gout developing post-TURP myocardial infarction	We analyze pre-operative diagnosed gout rate in patients who had myocardial infarction after the surgery of TURP.	within 12 months after the first admission for TURP
Primary	Number of patients with pre-operative diagnosed hypertension developing post-TURP myocardial infarction	We analyze pre-operative diagnosed hypertension rate in patients who had myocardial infarction after the surgery of TURP.	within 6 months after the first admission for TURP
Primary	Number of patients with pre-operative diagnosed hypertension developing post-TURP myocardial infarction	We analyze pre-operative diagnosed hypertension rate in patients who had myocardial infarction after the surgery of TURP.	within 12 months after the first admission for TURP
Primary	Number of patients with pre-operative diagnosed heart disease history developing post-TURP myocardial infarction	We analyze pre-operative diagnosed heart disease rate in patients who had myocardial infarction after the surgery of TURP.	within 6 months after the first admission for TURP
Primary	Number of patients with pre-operative diagnosed heart disease history developing post-TURP myocardial infarction	We analyze pre-operative diagnosed heart disease rate in patients who had myocardial infarction after the surgery of TURP.	within 12 months after the first admission for TURP
Primary	Number of patients with pre-operative diagnosed stroke history developing post-TURP myocardial infarction	We analyze pre-operative diagnosed stroke rate in patients who had myocardial infarction after the surgery of TURP.	within 6 months after the first admission for TURP
Primary	Number of patients with pre-operative diagnosed stroke history developing post-TURP myocardial infarction	We analyze pre-operative diagnosed stroke rate in patients who had myocardial infarction after the surgery of TURP.	within 12 months after the first admission for TURP
Primary	Number of patients with pre-operative diagnosed liver cirrhosis history developing post-TURP myocardial infarction	We analyze pre-operative diagnosed liver cirrhosis rate in patients who had myocardial infarction after the surgery of TURP.	within 6 months after the first admission for TURP
Primary	Number of patients with pre-operative diagnosed liver cirrhosis history developing post-TURP myocardial infarction	We analyze pre-operative diagnosed liver cirrhosis rate in patients who had myocardial infarction after the surgery of TURP.	within 12 months after the first admission for TURP
Primary	Number of patients with pre-operative diagnosed chronic obstructive pulmonary disease developing post-TURP myocardial infarction	We analyze pre-operative diagnosed chronic obstructive pulmonary disease rate in patients who had myocardial infarction after the surgery of TURP.	within 6 months after the first admission for TURP
Primary	Number of patients with pre-operative diagnosed chronic obstructive pulmonary disease developing post-TURP myocardial infarction	We analyze pre-operative diagnosed chronic obstructive pulmonary disease rate in patients who had myocardial infarction after the surgery of TURP.	within 12 months after the first admission for TURP
Primary	Number of patients with pre-operative diagnosed asthma developing post-TURP myocardial infarction	We analyze pre-operative diagnosed asthma rate in patients who had myocardial infarction after the surgery of TURP.	within 6 months after the first admission for TURP
Primary	Number of patients with pre-operative diagnosed asthma developing post-TURP myocardial infarction	We analyze pre-operative diagnosed asthma rate in patients who had myocardial infarction after the surgery of TURP.	within 12 months after the first admission for TURP
Secondary	Number of patients who had post-operative myocardial infarction after receiving general anesthesia for TURP	Number of patients who had post-operative myocardial infarction after receiving general anesthesia for TURP	within 6 months after the first admission for TURP
Secondary	Number of patients who had post-operative myocardial infarction after receiving neuraxial anesthesia for TURP	Number of patients who had post-operative myocardial infarction after receiving neuraxial anesthesia for TURP	within 6 months after the first admission for TURP
Secondary	Number of patients who did not have post-operative myocardial infarction after receiving general anesthesia for TURP	Number of patients who did not have post-operative myocardial infarction after receiving general anesthesia for TURP	within 12 months after the first admission for TURP
Secondary	Number of patients who did not have post-operative myocardial infarction after receiving neuraxial anesthesia for TURP	Number of patients who did not have post-operative myocardial infarction after receiving neuraxial anesthesia for TURP	within 12 months after the first admission for TURP