Anesthesia Clinical Trial
Official title:
1-1-12 Wash-in for Desflurane Low Flow Anesthesia
We propose a new wash-in technique for desflurane low flow anesthesia with fresh gas flow of
O2:N2O 1:1 L/min with desfluraene 12%.
The objective of this study is to identify time to achieve alveolar concentration of
desflurane at1, 2, 3, 4, 5 and 6%.
The benefits of low flow anesthesia are economic, less pollution, more heat and humidity
preservation but it requires appropriate wash-in phase. The current wash-in protocols are
complicated and time consuming. We propose a new 1-1-12 desflurane wash-in protocol which is
more simple and predictable.
The objective of this study is to identify time to achieve alveolar concentration of
desflurane at 1, 2, 3, 4, 5 and 6% with 1-1-12 wash-in protocol.
All patients will receive iv propofol 2 mg/kg as induction agent and succinyl choline 1.5
mg/kg for intubation. Then the ventilation will be controlled to achieve end-tidal CO2 30-35
mmHg with O2:N2O 1:1 L/min with desflurane 12%. Time to achieve alveolar concentration of
desflurane at 1, 2, 3, 4, 5 and 6% will be recorded and analyzed. After that, the
concentration of desflurane and anesthetic technique will be adjusted to requirement of
anesthesiologist.
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