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NCT ID: NCT03725228 Completed - Pain Clinical Trials

Lidocaine Compared to Magnesium Sulfate to Prolong Spinal Anesthesia: Non-inferiority Randomized Clinical Trial

Start date: November 7, 2018
Phase: Phase 4
Study type: Interventional

This study evaluates the addition of continuous infusion of lidocaine or continuous infusion of magnesium sufate in the duration of spinal anesthesia.

NCT ID: NCT03723109 Completed - Anesthesia Clinical Trials

Airway Management During TCI vs RSI Anesthesia Induction

Start date: October 29, 2018
Phase:
Study type: Observational

The aims of this observational study is to evaluate and compare feasibility of airway management during standardized TCI and RSI anesthesia induction.

NCT ID: NCT03722940 Completed - Anesthesia Clinical Trials

Role of Magnesium in Pediatric Cochlear Implant

Start date: June 1, 2014
Phase: Phase 4
Study type: Interventional

To determine the efficiency of addition of magnesium sulfate to total intravenous anesthesia (TIVA) in optimizing the surgical field during pediatric cochlear implant surgery. Also its effects on the intraoperative evoked stapedial reflex thresholds (ESRT) and the intraoperative anesthetic requirements were evaluated.

NCT ID: NCT03713008 Completed - Anesthesia Clinical Trials

Assessment Of Carotid Flow During General Anesthesia

Start date: October 22, 2018
Phase: N/A
Study type: Interventional

Proper identification of patients who would benefit from fluid infusion (fluid responsiveness) is one of the most crucial challenges in anaesthesia and critical care. Reliability of several invasive measurements used for this purpose for many years have been questioned recently. The study will evaluate consistency between carotid artery flow derivatives and standard haemodynamic measurement (LIDCO rapid) in navigation of intraoperative fluid therapy.

NCT ID: NCT03711981 Completed - Anesthesia Clinical Trials

Laparascopic TAP and Hysterectomy Trial #2

TAP2
Start date: January 27, 2016
Phase: N/A
Study type: Interventional

More than 600,000 hysterectomies are performed in the United States each year, making it the most common non-obstetric major surgery performed on women1. Estimates suggest that at least 30% of hysterectomies are performed laparoscopically or robotically with an increasing trend toward minimally invasive approaches2. While a minimally invasive approach certainly provides improved recovery, patients still experience substantial pain and most require opiate medications for pain control. Incorporating a multimodal approach to postoperative pain management through the use of field nerve blocks is potentially an ideal way to enhance recovery and minimize the need for narcotic pain medications. Over the past decade, the use of Transversus Abdominis Plane (TAP) blocks as an adjunct for postoperative pain management has gained in popularity. First described in 2001 by Dr. Rafi of Limerick3, Ireland, TAP blocks are now typically performed by an anesthesiologist with the use of ultrasound guidance. The transversus abdominis plane is the neurovascular plane between the aponeurosis of the internal oblique and transversus abdominis muscles. Herein lie the afferent nociceptor nerve endings of T7-L1. Injection of a 20-30cc volume of anesthetic into this plane causes a sensory nerve block to the ipsilateral antero-abdominal wall from the costal margin to the symphysis pubis4. Clinical trials have documented the validity of using TAP blocks for both open and laparoscopic procedures and verified their use for postsurgical pain relief. Studies have demonstrated that TAP blocks for both open and laparoscopic hysterectomies are safe and efficacious5, 6. In 2011, De Oliveira et al. demonstrated improved quality of recovery for women undergoing preoperative ultrasound guided TAP infiltration with ropivacaine at the time of laparoscopic hysterectomy7.

NCT ID: NCT03711734 Completed - Anesthesia Clinical Trials

Acupuncture ACL (Anterior Cruciate Ligament)

Start date: November 1, 2018
Phase: N/A
Study type: Interventional

Acupuncture research in regards to PONV has been fairly well established, however, studies about perioperative pain control and acupuncture are a little more murky. In 2008, a meta analysis looked at randomized controlled studies and found that while acupuncture was shown to decrease pain, there were limitations including credible placebo or sham intervention, and thus, blinding. The main purpose of this feasibility trial is to determine whether or not adequate blinding is possible in the intraoperative setting with the patient sedated.

NCT ID: NCT03709979 Completed - Anesthesia Clinical Trials

Effect Of Position On Laryngeal Visualisation With The C-Mac Videolaryngoscope

Start date: January 21, 2019
Phase: N/A
Study type: Interventional

The aim of this study is to demonstrate the effect of C-Mac videolaryngoscopy with Miller Blade size 0 and 1 on the intubation conditions in children less than 2 years age with a roll inserted under the shoulders.

NCT ID: NCT03706755 Completed - Anesthesia Clinical Trials

Comparison of Two Doses of Norepinephrine in Preventing Hypotension After Spinal Anesthesia

Start date: May 3, 2018
Phase: Phase 4
Study type: Interventional

The purpose of the study is to determine the more effective intravenous bolus of norepinephrine for maintaining blood pressure during a spinal anesthesia for a cesarean delivery with the fewer side effects. Low blood pressure has been shown to decrease uterine perfusion and foetal outcomes during cesarean delivery under spinal anesthesia. For elective or semi-urgent cesarean delivery, all participants will receive spinal anesthesia with a local anesthetic and either sufentanil or fentanyl. This study plans to enroll 124 pregnant women. Patients will be randomly assigned according to a computer generated system to be in one of two groups.

NCT ID: NCT03700970 Completed - Anesthesia Clinical Trials

Comparing Local Anesthetics for TAP Block During Abdominally-based Free Flap for Breast Reconstruction

Start date: June 13, 2019
Phase: Phase 4
Study type: Interventional

This study will compare the efficiency of transversus abominus plane (TAP) block using liposomal bupivacaine versus plain bupivacaine that is administered in the operating room under ultrasound guidance prior to the in patients undergoing abdominally-based free flap breast reconstruction at Vanderbilt University Medical Center.

NCT ID: NCT03681574 Completed - Anesthesia Clinical Trials

Gabapentin as Preanesthetic Medication to Fast Procedures in Pediatric´s Oncology

Start date: July 1, 2017
Phase: Phase 4
Study type: Interventional

This study is a clinical trial, prospective, randomized and double-blinded. Placebo, Gabapentin syrup at 15 mg/kg, and Gabapentin syrup at 30 mg/kg were administered to reduce agitation before and after in children submitted procedures (myelogram or lumbar puncture) among 1 and 6 years.