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Anesthesia clinical trials

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NCT ID: NCT05706857 Recruiting - Surgery Clinical Trials

Evaluation of the Clinical Impact of Ultra Fast-Track in Patients Undergoing Cardiac Surgery

CARDU-FAST
Start date: January 22, 2023
Phase: N/A
Study type: Interventional

Single center randomized clinical trial. The main aim is to demonstrate the superiority at the clinical level of the ultra fast-track programs versus conventional early postoperative extubation in patients undergoing cardiac surgery.

NCT ID: NCT05692167 Recruiting - Anesthesia Clinical Trials

Dexmedetomidine in Topical Versus Peribulbar Anesthesia for Cataract Surgery

Start date: July 15, 2023
Phase: Phase 2
Study type: Interventional

The aim of this study is to compare efficacy of dexmedetomidine as an additive to topical versus peribulbar anesthesia for cataract surgery

NCT ID: NCT05688943 Recruiting - Anesthesia Clinical Trials

Comparative Analysis of Spinal Anesthesia Versus General Anesthesia for vNOTES

Start date: March 1, 2023
Phase: N/A
Study type: Interventional

This study compares general anesthesia and spinal anesthesia for vNOTE tubal sterilization. A direct comparison of these methods has not been done before for this surgical approach. Investigators will aim to compare the two methods to determine the differences in perioperative complications, postoperative pain, postoperative nausea and vomiting, and the time to get the patient ready for discharge from the recovery room.

NCT ID: NCT05681572 Recruiting - Anesthesia Clinical Trials

Effect of Sedative and Anxiolytic Premedication on Children Experience After General Anesthesia

pediaPREM
Start date: April 18, 2023
Phase: Phase 3
Study type: Interventional

Children undergoing general anesthesia for surgery commonly need sedative and anxiolytic premedication but little clinical evidence supports is benefit for children older than 7 years old. The aim of this prospective randomized clinical trial is to assess the impact of pharmacologic premedication on perioperative children experience.

NCT ID: NCT05668689 Recruiting - Anesthesia Clinical Trials

URAISE: Ultrasound Regional Anaesthesia Interpretation Skill Evaluation

URAISE
Start date: February 13, 2022
Phase: N/A
Study type: Interventional

Prospective study based on psychometric principles.# To generate a validated test of ultrasound guided regional anaesthesia that can used to differentiate reliably between users of different skill levels. Primary outcome: Development of a validated, reliable and defensible tool to test ultrasound guided regional anaesthesia image interpretation skills. Secondary outcomes: Development a validated, reliable and defensible assessment tool assessing anatomical, clinical knowledge and the performance of ultrasound guided regional anaesthesia: Assessment of anatomical knowledge relevant to performing a local anaesthetic injection around peripheral nerves Assessment of clinical knowledge relevant to regional anaesthesia required to perform a local anaesthetic injection around peripheral nerves Assessment of knowledge relating to the performance of an ultrasound-guided local anaesthetic injection around peripheral nerve

NCT ID: NCT05664386 Recruiting - Anesthesia Clinical Trials

Effect of Ciprofol Infusion for Induction and Maintenance on Hemodynamics and Postoperative Recovery

Start date: April 10, 2023
Phase: Phase 4
Study type: Interventional

To study the Effect of Ciprofol Infusion for Induction and Maintenance of anesthesia on Hemodynamics and Postoperative Recovery in Patients Undergoing Thoracoscopic Lobectomy:a randomized, controlled trial.

NCT ID: NCT05663242 Recruiting - Lung Cancer Clinical Trials

The Effects of Using Different Anesthetics on the Prognosis of Primary Lung Tumors and Its Mechanism of Action

Start date: December 27, 2022
Phase: Phase 4
Study type: Interventional

This is a two-arm, parallel-group randomized clinical trial. Routine perioperative care would be performed in volunteers with primary early lung cancer. The study will enroll approximately 300 volunteers to compare the progression-free or overall survival in patients undergoing video-assisted thoracoscopic surgery (VATS) for primary lung tumors between propofol and sevoflurane for the maintenance of anesthesia.

NCT ID: NCT05657028 Recruiting - Anesthesia Clinical Trials

Dexmedetomidine Versus Lidocaine in Attenuating Airway Reflexes During Recovery of Thyroidectomy Patients

Start date: September 1, 2022
Phase: N/A
Study type: Interventional

It is widely believed that most of the patients experience a cough upon emergence from general anesthesia, due to many causes including the presence of an endotracheal tube, uncleared secretions and anesthetic gas. Cough during tracheal extubation may lead to several complications, such as hypertension, tachycardia and postoperative bleeding. In this study the investigators are going to compare the effectiveness of intravenous Dexmedetomidine and intravenous lidocaine in attenuating the air way reflexes and coughing during recovery of thyroidectomy patients.

NCT ID: NCT05655806 Recruiting - Anesthesia Clinical Trials

Effect of Aminophylline Bolus Versus Infusion on Recovery Time in Patients Undergoing Lumbar Spine Surgery

Start date: December 30, 2022
Phase: Phase 4
Study type: Interventional

To determine optimal dose, method and time of administration of aminophylline to enhance the recovery from general anesthesia. andTo estimate the recovery time from isoflurane closure in each group. We hypothesize that starting administration of loading and maintenance dose of aminophylline half an hour before discontinuing isoflurane will shorten the duration needed to extubate patients undergoing lumbar disc surgery. We hypothesized that it will yield superior results compared to bolus administration after discontinuing isoflurane.

NCT ID: NCT05654402 Recruiting - Anesthesia Clinical Trials

Non-invasive Measurement of Arterial Stiffness

NIVOP
Start date: February 10, 2023
Phase:
Study type: Observational

Reducing the risk of perioperative cardiovascular complications is a major issue for anesthesiology practice and research. Carotid-Femoral Pulse Wave Velocity (PWVcf)is a predictive, early and independent biomarker of cardiovascular events. Despite the unanimous support for PWVcf, it has not been widely used in routine clinical practice because of the complexity of the measurement method. Our team has developed a method to estimate PWVcf continuously in the operating room from the data obtained by the usual monitoring: an electrocardiogram (ECG), a digital photoplethysmography (PPG) and an oscillometric brachial sphygmomanometer for non-invasive blood pressure measurement (NIP). The objective of this study is to validate, during anesthesia, the method of estimation of PWV (obtained using the usual monitoring tools including the parameters derived from the SpO2 signal, NIBP and ECG) by comparing it to the reference method by measuring the carotid-femoral transit time obtained by Doppler effect. The measurement of the carotid-femoral transit time obtained by Doppler effect is totally non-invasive.