Anesthesia, Local Clinical Trial
Official title:
Evaluation of Second Esmarch Application on Intravenous Regional Anesthesia Effectiveness
NCT number | NCT03702387 |
Other study ID # | 1705426352 |
Secondary ID | |
Status | Recruiting |
Phase | N/A |
First received | |
Last updated | |
Start date | July 1, 2017 |
Est. completion date | June 2020 |
Intravenous regional anesthesia is a commonly used technique in the outpatient setting for short hand and upper extremity cases, such as carpal tunnel release or trigger finger release. The technique requires a tourniquet, Esmarch bandage, an intravenous line, and lidocaine. It can be performed and learned easily. The technique is safe and easy to perform, and it provides adequate anesthesia for short cases; however, there are still some cases in which adequate anesthesia is not achieved. One of the possible reasons for failure is that the local anesthetic (lidocaine) does not properly exit the veins to reach the interstitial space (where many nerves are located) to provide the nerve block. In this study, the investigators hypothesize that after application of lidocaine to the intravenous system, application of external pressure through the skin will facilitate tissue penetration and improve the block. The only research procedure being done is a re-application of the Esmarch bandage; all other procedures are Standard of Care.
Status | Recruiting |
Enrollment | 80 |
Est. completion date | June 2020 |
Est. primary completion date | June 2019 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | All |
Age group | 18 Years to 100 Years |
Eligibility |
Inclusion Criteria: - Male and female patients aged 18-100. - Short upper extremity or hand surgery (cases lasting less than 45 minutes). - Must be outpatient surgery. Exclusion Criteria: - Patients requesting to withdraw from the study. - Patients with a history of drug abuse or illicitly used controlled drugs or substances within the last year. |
Country | Name | City | State |
---|---|---|---|
United States | University of Arizona | Tucson | Arizona |
Lead Sponsor | Collaborator |
---|---|
University of Arizona |
United States,
Acalovschi I, Cristea T, Margarit S, Gavrus R. Tramadol added to lidocaine for intravenous regional anesthesia. Anesth Analg. 2001 Jan;92(1):209-14. — View Citation
Brown EM, McGriff JT, Malinowski RW. Intravenous regional anaesthesia (Bier block): review of 20 years' experience. Can J Anaesth. 1989 May;36(3 Pt 1):307-10. — View Citation
Dunbar RW, Mazze RI. Intravenous regional anesthesia: experience with 779 cases. Anesth Analg. 1967 Nov-Dec;46(6):806-13. — View Citation
Lai YY, Chang CL, Yeh FC. The site of action of lidocaine in intravenous regional anesthesia. Ma Zui Xue Za Zhi. 1993 Mar;31(1):31-4. — View Citation
Memis D, Turan A, Karamanlioglu B, Pamukçu Z, Kurt I. Adding dexmedetomidine to lidocaine for intravenous regional anesthesia. Anesth Analg. 2004 Mar;98(3):835-40, table of contents. — View Citation
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | IVRA Block Success Rate | This study hopes to compare the intravenous regional anesthesia (IVRA) block success rate between the experimental and control groups. The success rate will be defined as whether or not additional anesthesia is needed before or during surgery. | This outcome measure will only be measured for the duration of the surgical procedure. |
Status | Clinical Trial | Phase | |
---|---|---|---|
Completed |
NCT03663478 -
Continuous TQL Block for Elective Cesarean Section
|
Phase 4 | |
Completed |
NCT04513652 -
A Study of the Safety and Anesthetic Effect of AG-920 Topical Ophthalmic Solution
|
Phase 3 | |
Completed |
NCT05464862 -
The Effect of PPB Using 10, 20 and 30 ml of Lidocaine, Study on Volunteers
|
Phase 4 | |
Completed |
NCT04690647 -
The Efficacy of Suprainguinal Fascia Iliaca Compartment Block for Analgesia After Elective Total Hip Replacement.
|
N/A | |
Completed |
NCT03245359 -
Pain Management After TKA: Comparison of Short- and Long-term Nerve Blocks
|
N/A | |
Recruiting |
NCT06028126 -
Superficial Parasternal Intercostal Plane Block in Cardiac Surgery Trial
|
N/A | |
Not yet recruiting |
NCT05815563 -
Validation of Peripheral Perfusion Index in Predicting Successful Supraclavicular Brachial Plexus Block in Pediatrics
|
||
Completed |
NCT01418690 -
Changes in Tissue Oxygenation Following Regional Anesthesia
|
N/A | |
Suspended |
NCT03291691 -
Protective Nerve Stimulation in Regional Anesthesia
|
||
Not yet recruiting |
NCT03545516 -
Wound Infiltration as Part of an Opioid Free Pain Management Pathway Following Cesarean Delivery
|
Phase 2 | |
Not yet recruiting |
NCT05038007 -
Pain After Lung Cancer Surgery - Comparing Traditional Versus Prolonged Release Nerve Blockades
|
Phase 2 | |
Terminated |
NCT03672500 -
Perineal Local Infiltration Study
|
N/A | |
Enrolling by invitation |
NCT06057090 -
Do Therapy Dogs Improve Behavior and Reduce Anxiety in Pediatric Dental Patients?
|
N/A | |
Recruiting |
NCT05415865 -
The Effect of Local Anesthetic Solution in the Bladder Prior to Botox Injections in the Bladder
|
Phase 3 | |
Recruiting |
NCT06011005 -
Efficacy of Ethyl Chloride Topical Anesthesia Application on the Pain Perception During Intra-oral Injections in Children in Comparison to Benzocaine Gel.
|
N/A | |
Completed |
NCT04536311 -
Surgical Stabilization of Rib Fractures While Awake or Under Appropriate Sedation by Paravertebral Block
|
N/A | |
Completed |
NCT03600454 -
The Effect of Anesthesia on Perioperative Muscle Weakness and Neuro-endocrine Stress Response
|
N/A | |
Recruiting |
NCT03159338 -
Platelet-rich Fibrin on Nerve Regeneration After Bilateral Sagittal Split Osteotomy
|
N/A | |
Completed |
NCT02966067 -
A Split Mouth Trial to Compare Microneedles vs. Standard Needles in Dental Anaesthetic Delivery
|
N/A | |
Completed |
NCT03305666 -
Trial of Injected Liposomal Bupivacaine vs Bupivacaine Infusion After Surgical Stabilization of Rib Fractures
|
Phase 4 |