Ciprofol vs Propofol for Reducing Hypoxia Incidence in ERCP

Status Not yet recruiting

Clinical Trial Summary

Intravenous anesthesia has been widely used in endoscopic retrograde cholangiopancreatography (ERCP). In the past decade, many practices have been carried out under the propofol-based monitored anesthesia care without endotracheal intubation in patients undergoing ERCP. Ciprofol is a newly developed intravenous anesthetic with a potency 4-5 times than that of propofol. Ciprofol seems a promising anesthetic agent for intravenous anesthesia but the evidence supported its application in ERCP is still limited.

Clinical Trial Description

This is a prospective, randomized, double-blind trial comparing the incidence of hypoxia in the propofol versus ciprofol intravenous Anesthesia. A total 124 patients will be recruited and randomly assigned to either the propofol or the ciprofol group. The primary outcome is the proportion of patients experiencing hypoxia. The secondary outcomes include: the incidence of hypotension in perioperative period; the incidence of conversion from intravenous anesthesia to general anesthesia; sedation-related procedure interruption; CO2 accumulation during operation; Patients' satisfaction with anesthesia and postoperative recovery / VAS score / incidence of nausea and vomiting; the incidence of intraoperative and postoperative adverse events, such as adverse excretion, severe hypoxemia, severe circulatory dysfunction; length of stay and mortality within 30 days after operation. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT06015074
Study type	Interventional
Source	RenJi Hospital
Contact	Peiying Li, Doctor
Phone	15800616866
Email	peiyingli.md@gmail.com
Status	Not yet recruiting
Phase	N/A
Start date	October 1, 2023
Completion date	June 30, 2024

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