Hemodynamic Stability During Induction of Anaesthesia

Status Completed

Clinical Trial Summary

The study aim is to investigate if preoperative volume bolus based on lean body weight could preserve mean arterial pressure during target controlled infusion of anaesthesia (TCI) or rapid sequence induction of anaesthesia (RSI) in non-cardiac, non-morbidly obese surgery.

Clinical Trial Description

40 individuals are enrolled to TCI and RSI groups respectively. The randomization process for preoperative fluid bolus prior to induction of anaesthesia is conducted in respective group at the day of surgery. Preoperative colloid fluid therapy (6 ml/kg LBW, Gelofusine™, Fresenius Kabi Ab, Sweden) is infused rapidly before non-invasive baseline blood pressure (NIBP) measurements in twenty individuals in each group. No other intravenous fluids before induction of anaesthesia.

NIBPs, pulse frequency, peripheral saturation (SpO2) are registered and collected 20 minutes post induction. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT03394833
Study type	Interventional
Source	Umeå University
Contact
Status	Completed
Phase	N/A
Start date	November 20, 2017
Completion date	April 30, 2019

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