Postoperative Consequences of Intraoperative NOL Titration

Status Completed

Clinical Trial Summary

To demonstrate that intraoperative NOL-guided titration of fentanyl improves initial recovery characteristics.

Clinical Trial Description

Previous work has shown that NOL (Nociception Level) accurately quantifies nociception during general anesthesia.6 Presumably, titrating opioids to NOL will therefore provide individual guidance so that patients will be given about the right amount. Patient given the right amount will presumably awaken quickly when anesthesia is done, and have good initial pain control in the PACU (Post-Anesthesia Care Unit). To the extent that NOL titration facilitates optimal opioid dosing, patients are likely to have better PACU experiences - which would be an important outcome that clinicians and regulators are likely to take seriously. ;

Study Design

Related Conditions & MeSH terms

Anesthesia; Adverse Effect

Clinical Trial Details

NCT number	NCT04679818
Study type	Interventional
Source	The Cleveland Clinic
Contact
Status	Completed
Phase	Phase 3
Start date	December 30, 2020
Completion date	January 10, 2023

View Details

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