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NCT03560921 Clinical Trial

Urinary NGAL Acute Kidney Injury After Stored Red Blood Cells Transfusion in Critically Ill Patients.

Anemia Clinical Trial

Official title:
The Association of NGAL With the Development of Acute Kidney Injury After Stored Red Blood Cells Transfusion in Critically Ill Patients.

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT03560921
Other study ID # KA-13115
Secondary ID
Status Completed
Phase
First received
Last updated
Start date June 2, 2017
Est. completion date December 5, 2017

Study information
Verified date June 2018
Source Kasr El Aini Hospital
Contact n/a
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

The study aims to explore the association of the novel urinary bio marker NGAL with the age of PRBCs(packed red blood cells) transfusion in critically ill patients.

Description:

The investigators will measure the urinary NGAL in all patients who received blood transfusion in the intensive care unit during the study period. The age of PRBCs transfusion will be correlated with the incidence of AKI. The rise of NGAL and serum creatinine will be used to diagnose AKI (Acute Kidney Injury).

Recruitment information / eligibility
Status Completed
Enrollment 147
Est. completion date December 5, 2017
Est. primary completion date December 5, 2017
Accepts healthy volunteers No
Gender All
Age group 18 Years and older
Eligibility Inclusion Criteria:

- Any patients admitted to the intensive care unit.

Exclusion Criteria:

- patients who have established AKI at the time of recruitment

Study Design

Related Conditions & MeSH terms

Intervention

Diagnostic Test:
• urinary NGAL
measurement urinary NGAL using the ARCHITECT technique

Locations
Country Name City State
Egypt Cairo university hospitals Cairo

Sponsors (1)
Lead Sponsor Collaborator
Kasr El Aini Hospital

Country where clinical trial is conducted

Egypt, 

Outcome
Type Measure Description Time frame Safety issue
Primary Incidence of AKI Diagnosis of AKI by rise of serum creatinine within 30 days
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