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Anemia of Chronic Kidney Disease clinical trials

View clinical trials related to Anemia of Chronic Kidney Disease.

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NCT ID: NCT05699109 Completed - Clinical trials for Chronic Renal Failure

Erythropoiesis Stimulating Agents for Anemia Management in Egyptian Hemodialysis Patients

Start date: January 1, 2021
Phase:
Study type: Observational

This observational study aims to compare long-acting darbepoetin alpha versus short-acting epoetin alpha erythropoietin-stimulating agents in Egyptian hemodialysis patients. The main questions aim to answer are: - What are the effectiveness and safety of long- acting versus short-acting erythropoietin-stimulating agents in Egyptian hemodialysis patients? - What is the cost-effectiveness of long- acting versus short-acting erythropoietin-stimulating agents in Egyptian hemodialysis patients? Participants will be divided into 2 groups; epoetin alfa (short-acting ESA), Eprex group, and darbepoetin alfa (long-acting ESA), Aranesp group for six month study period.

NCT ID: NCT05698420 Completed - Depressive Disorder Clinical Trials

Investigation of the Effects of Medium Cut-off Dialyzers Versus High-Flux Dialyzers on Clinical and Laboratory Parameters of Prevalent Hemodialysis Patients

Start date: March 1, 2020
Phase:
Study type: Observational

In this study, the investigators aimed to observe the effects of medium cut-off dialysis filters and high-flux dialysis filters on malnutrition inflammation score, uremic itching, restless leg syndrome, anemia, and ESA treatment, which are prominent complications in hemodialysis, and routine follow-up parameters.

NCT ID: NCT04959578 Completed - Clinical trials for Anemia of Chronic Kidney Disease

Comparison of Darbepoetin Alpha and Recombinant Human Erythropoietin for Treatment of Anemia in Children With Chronic Kidney Disease

Start date: February 1, 2018
Phase: Phase 4
Study type: Interventional

The present study was designed to determine whether or not darbepoetin alfa is non-inferior to recombinant human erythropoietin in the treatment of anemia in children with chronic kidney disease stage 3-5 (on or not on dialysis).

NCT ID: NCT04667533 Completed - Chemotherapy Effect Clinical Trials

Desidustat in the Treatment of Chemotherapy Induced Anemia

Start date: November 11, 2020
Phase: Phase 1
Study type: Interventional

This is a Phase 1, Open-label, Single Dose, Study to Evaluate the Safety, Tolerability and Pharmacokinetics of Desidustat for treatment of anemia in patients receiving chemotherapy.

NCT ID: NCT04655027 Completed - Clinical trials for Anemia of Chronic Kidney Disease

A Study to Investigate the Effect of Roxadustat Versus Recombinant Human Erythropoietin (rHuEPO) on Oral Iron Absorption in Chinese Patients With Anemia of Chronic Kidney Disease (CKD)

Start date: February 22, 2021
Phase: Phase 4
Study type: Interventional

This is a Phase IV, randomized, active-controlled, open-label, parallel design, multicenter prospective study to evaluate the effect of roxadustat versus rHuEPO treatment on the gastrointestinal (GI) iron absorption in patients with anemia of Stage 4 and Stage 5 CKD.

NCT ID: NCT04543812 Completed - Clinical trials for Anemia of Chronic Kidney Disease

PBF-1681 (Ferric Citrate) for the Treatment of IDA in Patients With NDD-CKD

Start date: October 14, 2020
Phase: Phase 3
Study type: Interventional

To assess the safety and effectiveness of PBF-1681 for the treatment of Iron Deficiency Anemia in patients with Non-Dialysis Dependent Chronic Kidney Disease.

NCT ID: NCT04027517 Completed - Clinical trials for Anemia of Chronic Kidney Disease

A Study to Evaluate Efficacy and Safety of JTZ-951 Compared to Darbepoetin Alfa in Korean Renal Anemia Patients Receiving Hemodialysis.

Start date: January 15, 2019
Phase: Phase 3
Study type: Interventional

JTZ-951 is a currently being developed as a treatment for renal anemia. This study aims to evaluate the efficacy and safety of JTZ-951 following a switch from erythropoiesis-stimulating agent (ESA) in Korean subjects receiving HemoDialysis with renal anemia. This study is a Phase III, open, active-controlled, parallel-group, multi-center study. The total duration of the study will be 30 weeks including screening, treatment and follow-up.

NCT ID: NCT03731741 Completed - Clinical trials for Anemia of Chronic Kidney Disease

Does Oral Pentoxifylline Administration Improve Hemoglobin in Hemodialysis Patients?

Start date: November 1, 2017
Phase: Phase 2
Study type: Interventional

Our study investigated the effect of using a known drug used in intermittent claudication (named pentoxifylline) as an adjuvant to erythropoietin stimulating agents to improve anemia of hemodialysis patients.

NCT ID: NCT03633656 Completed - Clinical trials for Renal Insufficiency, Chronic

Iron Dosing Pilot Study Using Model Predictive Control

Start date: February 1, 2019
Phase: Phase 4
Study type: Interventional

This is a pilot study to test the utility of an integrated approach in the management of the anemia of chronic kidney disease through the administration of both an erythropoietic stimulating agent and iron. Subjects will be studied for 6 months during which all iron dosing will be recommended using a computer based tool using model predictive control. Comparisons will be made to the 6 months prior to enrollment in to the study.

NCT ID: NCT03431623 Completed - Clinical trials for Anemia of Chronic Kidney Disease

CKD-11101 Phase 3 SC Study

Start date: May 2015
Phase: Phase 3
Study type: Interventional

The aim of this study was to compare and evaluate efficacy and safety of subcutaneous CKD-11101 versus Darbepoetin alfa in patients who have renal anemia not on dialysis.