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Analgesia clinical trials

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NCT ID: NCT04259502 Not yet recruiting - Analgesia Clinical Trials

Rhomboid Intercostal Block vs Erector Spina Plan Block for Peri-operative Analgesia in Mastectomy

Start date: February 2020
Phase: N/A
Study type: Interventional

Effectiveness of erector spinae plane block for analgesia in breast surgery was documented in previous studies. Rhomboid intercostal block may be beneficial for analgesia in breast surgery. The aim of this study is to compare the peri-operative analgesic effect of rhomboid intercostal block with erector spinae plane block in mastectomy operation. This trial was designed as prospective randomized single-blind study. The included patients will be assigned into two groups: RIB-Group where the patients will receive ultrasound-guided rhomboid intercostal block and ESP-Group where the patients will receive ultrasound-guided erector spinae plane block prior to the operation. Primary outcome will be peri-operative pain scores and secondary outcomes will be peri-operative opioid consumption and peri-operative hemodynamic effect of these blocks.

NCT ID: NCT04143542 Not yet recruiting - Analgesia Clinical Trials

Trunks Body Blocks for Postoperative Analgesia in Abdominal Surgery

Start date: April 23, 2020
Phase: N/A
Study type: Interventional

This study aims to the comparison of Quadratus Lumborum Block 2 and Transversus Abdominis Plan Block for Postoperative Analgesia in Abdominal Surgery

NCT ID: NCT03749915 Not yet recruiting - Analgesia Clinical Trials

Ametop Compared to Ametop With Pain Ease Spray

Start date: November 20, 2018
Phase: N/A
Study type: Interventional

The investigators propose to examine if Pain Ease spray, used as an adjunct to the topical anesthetic Ametop Gel, can improve the percentage of pain-free IV starts.

NCT ID: NCT03628040 Not yet recruiting - Analgesia Clinical Trials

Erector Spinae Plane Block for Video-assisted Thoracoscopic Surgery

Start date: September 1, 2019
Phase: Phase 3
Study type: Interventional

Video-Assisted Thoracoscopic Surgery (VATS) is a minimally invasive surgery that utilizes camera based scopes and specialized instruments through keyhole sized ports to remove lesions in the thoracic cavity. Despite reduced surgical trauma compared to the traditional thoracotomy approach, patients continued to experience moderate to severe postoperative pain. Pain medication such as opioids is commonly utilized for postoperative pain control but is associated with side effects. The use of nerve blocks, such as the recently described erector spinae plane block (ESPB) has been shown in case reports to reduce pain and thus has the potential to improve patient recovery and decrease the risk of pulmonary complication. This study aims to investigate the analgesic effect of ESPB in managing pain following VATS.

NCT ID: NCT03060265 Not yet recruiting - Analgesia Clinical Trials

Protective Analgesia in Caesarean Section Using Intravenous Paracetamol

Start date: March 2017
Phase: N/A
Study type: Interventional

Protective analgesia in caesarean section using intravenous paracetamol: A prospective randomised controlled trial. Cesarean section a common surgical procedure in women. The parturients undergoing CS experience severe to moderate postoperative pain. Pain relief is very important to the patient as it causes discomfort which affects hemodynamic intraoperative and increases the risk of postoperative complications. Analgesia is crucial to postoperative recovery. Aims: To investigate the efficacy of combined administration of paracetamol, as protective multimodal analgesia, and standard spinal anesthesia in the reduction of postoperative pain following cesarean section. Sixty adult Parturients undergoing CS will participate in a single-centered, randomized, double-blinded, placebo-controlled trial divided into 2 groups 30 each. The intervention group will receive 1 gr of intravenous paracetamol in 100 ml normal saline only 15 minutes prior to spinal anesthesia induction. The control group will receive 100 ml normal saline IV identical in size and shape and manner to the experimental group, 15 minutes prior to induction of spinal anesthesia. We will measure postoperative Visual Analog Scale (VAS) pain score, postoperative time to analgesia in PACU and number of postoperative analgesic doses within 24 hours.

NCT ID: NCT03016650 Not yet recruiting - Analgesia Clinical Trials

Opioid-sparing Effect of Intravenous Ibuprofen

Start date: January 2017
Phase: Phase 4
Study type: Interventional

The investigators aimed to evaluate tramadol-sparing effect of intravenous (IV) ibuprofen in patients undergoing percutaneous nephrolithotomy (PCNL).

NCT ID: NCT02549118 Not yet recruiting - Analgesia Clinical Trials

Tenoxicam for Intrapartum Analgesia

Start date: September 2015
Phase: Phase 2
Study type: Interventional

The aim of this study is to assess whether tenoxicam is as effective as pethidine for analgesia during the first stage of labor.

NCT ID: NCT02190760 Not yet recruiting - Analgesia Clinical Trials

Comparison Between Perineural and Systemic Effect of Dexamethasone for Interscalene Brachial Plexus Block.

Start date: September 2014
Phase: N/A
Study type: Interventional

The addition of dexamethasone (DxaM) to local anesthetic may significantly prolong the duration of a block. The aim of this study is to determine whether this a systemic or local effect.

NCT ID: NCT01684774 Not yet recruiting - Analgesia Clinical Trials

Comparison Between Ultrasound-guided and Landmark-guided Ankle Blocks

Start date: December 2012
Phase: N/A
Study type: Observational

The investigators will be comparing ultrasound-guided (USG) ankle block and anatomic landmark-guided (ALG) ankle block to determine which of these procedures is better in surgical anesthesia and in postoperative pain relief.

NCT ID: NCT01201499 Not yet recruiting - Pain Clinical Trials

Comparing the Outcome of Two Intraoperative Analgesia Techniques After Hepato-pancreato-biliary Surgery

Start date: November 2010
Phase: N/A
Study type: Interventional

Inadequate pain control after abdominal procedures may lead to adverse postoperative outcome. Epidural analgesia is currently an accepted technique in abdominal surgery, but its use has been limited in liver resections by postoperative coagulation disturbances and the possible increased risk of bleeding complications, including spinal hematoma. A range of alternative analgesic techniques can be used for major liver or pancreatic resections, including intrathecal morphine (single shot) administered immediately before surgery, and continuous administration of intravenous (IV) short-acting opioids, such as remifentanil, plus a single bolus of IV morphine. Postoperatively analgesia may be obtained by patient-controlled morphine analgesia (IV PCA). Both protocols have been demonstrated to provide satisfactory postoperative pain relief, and each has its unique advantages. However, to this end there is no data in the literature to show benefit from one regimen over the other. We therefore wish to determine whether there is a difference in analgesic efficacy between the two techniques, as optimizing perioperative pain relief in this rapidly expanding surgical field is of utmost importance. Our hypothesis is that continuous intraoperative IV analgesia with remifentanil followed by IV PCA morphine is not inferior to intrathecal morphine with respect to analgesia and ambulation outcome, and may provide an alternative, non-invasive intraoperative analgesic technique.