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Analgesia clinical trials

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NCT ID: NCT06187909 Recruiting - Analgesia Clinical Trials

US-Guided PECS II Block Versus MTP Block For Postoperative Analgesia Of MRM Sugery

Start date: March 1, 2024
Phase: N/A
Study type: Interventional

This study aims to compare the analgesic efficacies of the modified pectoral plane block (PECS II) and the midpoint transverse process to pleura block (MTP), after modified radical mastectomy (MRM) surgery during the first 24 hour post-operatively by using the Visual Analogue Scale.

NCT ID: NCT06183528 Recruiting - Analgesia Clinical Trials

Effects of Pericapsular Nerve Group Block on Postoperative Recovery for Total Hip Arthroplasty

Start date: September 1, 2023
Phase: N/A
Study type: Interventional

The hypothesis of this study is that patients who undergo PENG block in before Total Hip Artroplasthy (THA) surgery with spinal anesthesia will have reduced postoperative pain scores, less need for opioid analgesics and earlier mobilisation.

NCT ID: NCT06179641 Recruiting - Postoperative Pain Clinical Trials

Comparison of Two Different Regional Analgesia Techniques for Patients Undergoing Total Knee Arthroplasty

PIPACK
Start date: February 8, 2024
Phase: N/A
Study type: Interventional

The objective of this clinical trial is to compare two regional analgesia techniques in patients undergoing total knee arthroplasty: IPACK (Infiltration of local anesthetic between the Popliteal Artery and Capsule of the Knee) vs selective tibial nerve block. The main question is whether one of these peripheral blocks is more effective in reducing postoperative pain than the other. All patients will have a spinal block with an adductor canal block. One group will receive an IPACK block and the other group, a selective tibial nerve block. Postoperative pain scores and morphine consumption, among others, will be compared between groups.

NCT ID: NCT06177665 Recruiting - Postoperative Pain Clinical Trials

Comparison of Erector Spina Plan Block and Rhombodid Intercostal Block in Breast Surgery

Start date: July 1, 2023
Phase: N/A
Study type: Interventional

In this study, the investigators compared ultrasound-guided erector spinae plane (ESP) block and rhomboid intercostal block (RIB) on postoperative analgesic effect in unilateral breast surgery.

NCT ID: NCT06177652 Recruiting - Postoperative Pain Clinical Trials

Postoperative Analgesis for Pain Management After Thoracotomy

Start date: June 1, 2022
Phase: N/A
Study type: Interventional

Thoracotomy is among the most painful surgical procedures and can cause severe pain. Postoperative pain causes many complications. Therefore, pain management is important in patients undergoing thoracotomy. For this purpose, systemic analgesics are used along with ultrasound-guided nerve blocks in thoracotomy pain. The effectiveness of thoracic paravertebral block and serratus plane block in the treatment of post-thoracotomy pain will be evaluated by comparing their effectiveness and complications on postoperative pain. Since the epidural spread of the thoracic paravertebral block is more effective, the effectiveness of postoperative pain relief will be more effective

NCT ID: NCT06172465 Recruiting - Analgesia Clinical Trials

Comparison of OSTAP and EOIP Blocks in Laparoscopic Cholecystectomies

Start date: January 5, 2024
Phase: N/A
Study type: Interventional

Laparoscopic cholecystectomy (LC) surgery causes postoperative severe pain. As part of multimodal analgesia aimed at reducing postoperative opioid consumption and providing effective analgesia, ultrasound (US)-guided transversus abdominis plane block (TAP) and external oblique intercostal plane block (EOIPB) will be applied as regional anesthesia methods. There is no study in the literature comparing OSTAP and EOIP blocks, and our goal is to evaluate the analgesic effectiveness between OSTAP and EOIP blocks in LC surgeries.

NCT ID: NCT06156709 Recruiting - Analgesia Clinical Trials

Effect of Higher Volume and Lower Dose on Analgesic Quality During Labor Analgesia With Dural Puncture Epidural

Start date: November 20, 2023
Phase: N/A
Study type: Interventional

It is aimed in this study to compare the effect of using local anaesthetics in a higher volume and lower dose on the total anesthetic consumption and quality of labor analgesia with dural puncture epidural technique.

NCT ID: NCT06129032 Recruiting - Analgesia Clinical Trials

Comparing QLB Type I Block to Intraperitoneal Instillation Added to Wound Infiltration for Postoperative Cesarian Pain

Start date: November 1, 2023
Phase: N/A
Study type: Interventional

This study aimed to compare the efficacy of local anaesthetic infiltration into all layers of the anterior abdominal wall with peritoneal instillation and QLB type I for pain reduction in women undergoing elective cesarean section under spinal anaesthesia.

NCT ID: NCT06092073 Recruiting - Analgesia Clinical Trials

Bilateral Recto-Intercostal Fascial Plane Block in Epigastric Hernia Repair

Start date: October 21, 2023
Phase: N/A
Study type: Interventional

The aim of this study is to evaluate the efficacy and safety bilateral recto-intercostal fascial plane block (RIFPB) in epigastric hernia.

NCT ID: NCT06051227 Recruiting - Analgesia Clinical Trials

Fentanyl OR Esketamine for Traumatic PAIN (FORE-PAIN) Trial

FORE-PAIN
Start date: January 11, 2024
Phase: Phase 3
Study type: Interventional

Fentanyl and esketamine are both standard of care for treatment of acute severe traumatic pain in the prehospital setting in the Netherlands. However, it is not known whether they are equally effective and safe. It is also not known whether intranasal (IN) administration of fentanyl or esketamine is equally effective and safe as intravenous (IV) administration. The FORE-PAIN trial is a double-blind multi-arm randomized non-inferiority trial comparing Fentanyl IN, esketamine IV and esketamine IN (intervention arms) to fentanyl IV (comparator arm) for prehospital management of traumatic pain. The investigators hypothesize that all intervention arms provide analgesia that is non-inferior to the comparator arm, and that all study arms are equally safe.