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Analgesia clinical trials

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NCT ID: NCT04969133 Recruiting - Analgesia Clinical Trials

TAP Block Versus Local Anesthesia Wound Infiltration for Postoperative Pain Relief After Appendicectomy in Children

PABLO
Start date: July 30, 2021
Phase: N/A
Study type: Interventional

When performing laparoscopic appendectomy in children, regional anesthetic techniques are rou-tinely used concomitantly with general anesthesia. These techniques include local infiltration of the trocar wounds or transverse abdominal plane block (TAP block). In 2018, a position paper of the European Society of Pediatric Anaesthesiology advised for TAP block over local infiltration of the trocar wounds. However, there is no randomized study comparing both techniques in children. The aim of this study is to compare morphine consumption during the first 24 postoperative hours in children undergoing laparoscopic appendectomy and randomly allocated to either local infiltration of the trocar wounds or TAP block.

NCT ID: NCT04965194 Completed - Analgesia Clinical Trials

Ultrasound-guided Erector Spinae Block Versus Quadratus Lumborum Block for Laparotomies

Start date: July 15, 2021
Phase: N/A
Study type: Interventional

The study aimed to compare the effect of ESP block and QL block in preventing postoperative pain and decreasing analgesic consumption in patients scheduled for laparotomies. This prospective randomized controlled study will be done after obtaining ethics committee's permission and written informed consent of the patients 60 adult patients aged 18-60 years scheduled for open laparotomies under general anesthesia will be included in this study. According to the used technique, the patients will be randomly allocated into 3 parallel equal groups (20 patients in each one). Group I (ES group): the patients will receive bilateral ESP block. Group II (QL group): the patients will receive bilateral QL block. Group III (control group): the patients will not receive any regional block.

NCT ID: NCT04962152 Recruiting - Analgesia Clinical Trials

Naldebain and Video-assisted Thoracoscopic Surgery

Start date: July 7, 2021
Phase: Phase 4
Study type: Interventional

To evaluate the postoperative analgesic effect of combined use of Naldebain® and thoracic paravertebral block in thoracoscopic surgery

NCT ID: NCT04956718 Completed - Analgesia Clinical Trials

Breath Metabolomics of Placebo Effects, a Pilot Study

BMPE
Start date: October 21, 2021
Phase: N/A
Study type: Interventional

This study is to analyze the breath metabolome before and after the administration of a placebo in an established experimental pain procedure in healthy subjects in order to investigate placebo effects, and whether they induce any measurable changes at the metabolic level.

NCT ID: NCT04953507 Recruiting - Analgesia Clinical Trials

Evaluation of T2, T3 Sympathectomy for Postmastectomy Pain Syndrome by Pulse Oximeter

Start date: July 3, 2021
Phase: N/A
Study type: Interventional

The aim of the study is to compare the efficacy of T2, T3 sympathetic block using thermal radiofrequency versus chemical neurolysis in postmastectomy pain syndrome using perfusion index derived from pulse oximetry.

NCT ID: NCT04947345 Not yet recruiting - Postoperative Pain Clinical Trials

The Availability and Safety Study of Remimazolam Besylate for Injection on Sedation of ERAS Patients

Start date: September 1, 2021
Phase: Phase 3
Study type: Interventional

This trial intends to evaluate Remimazolam Besylate's availability and safety compared with propofol.

NCT ID: NCT04945512 Recruiting - Analgesia Clinical Trials

Efficacy of Epidural Analgesia in Lower Extremity Osteosarcoma

Start date: November 7, 2021
Phase: N/A
Study type: Interventional

In this study, the investigators aim to reduce complications in orthopedic malignancy surgeries and to increase the quality of life of patients who will be operated on.

NCT ID: NCT04931433 Completed - Analgesia Clinical Trials

Intravenous Lignocaine as an Analgesic Adjunct in Adolescent Idiopathic Scoliosis Surgery

IGNITE-AIS
Start date: December 24, 2020
Phase: Phase 4
Study type: Interventional

This is a single-center study comparing the effect of intravenous (IV) Lignocaine given throughout posterior spinal fusion surgery on the reduction of morphine usage during postoperative period in adolescent idiopathic scoliosis (AIS) patients.

NCT ID: NCT04928651 Completed - Analgesia Clinical Trials

Clonidine for Analgesia to Preterm Infants During Neonatal Intensive Care

Start date: April 6, 2018
Phase:
Study type: Observational

A prospective pharmacokinetic (PK), pharmacodynamic (PD) and pharmacogenetic (PG) observation study, including the PK/PD/PG relationship, in clonidine administered for analgesia and sedation to preterm newborn infants receiving neonatal intensive care. Phase 3 - therapeutic confirmatory study

NCT ID: NCT04921007 Completed - Analgesia Clinical Trials

Ultrasound Guided Sacral Erector Spinae Plane Block in Pediatric Anorectal Surgery

Start date: August 13, 2021
Phase: N/A
Study type: Interventional

This study will be conducted to evaluate efficacy of ultrasound guided sacral erector spinae plane block for postoperative analgesia in pediatric anorectal surgery in comparison to caudal block.