Comparison of Two Different Approach TAP Block on Pain Management of Laparoscopic Nephrectomy

Postoperative Pain, Acute Clinical Trial

Official title:

Comparison of Two Different Approach Ultrasound Guided TAP Block on Pain Management of Laparoscopic Nephrectomy: Posterior or Lateral Approach?

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT05188794
• Other study ID #: E1-21-1814
• Status: Completed
• Phase: N/A
• Start date: January 1, 2022
• Est. completion date: May 15, 2022

Study information

• Verified date: April 2024
• Source: Ankara City Hospital Bilkent
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Primary aim is to compare the effectiveness of the posterior approach Transversus abdominis plane block (P-TAP) and the lateral approach Transversus abdominis plane block (L-TAP) technique on the pain management of the laparoscopic nephrectomy in terms of visual analog pain scale and postoperative opioid consumption. Secondary aim is to compare complication rates of the two techniques.

Description:

Patients included in the study will be randomized into two groups (group L and group P) in the preoperative period. Following routine anesthesia induction TAP block will be applied to group L patients with the lateral approach technique, and to group P patients with the posterior approach technique. Regional block complications will be recorded. Standard laparoscopic nephrectomy surgical method will be applied. 1g of paracetamol and 4mg of dansetron will be administered to both groups 15 minutes before the end of the operation. The pain intensity of the patients will be questioned and VAS values will be recorded at 0, 1, 2, 6, 12 and 24 hours postoperatively.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 88
• Est. completion date: May 15, 2022
• Est. primary completion date: May 1, 2022
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years to 75 Years

Eligibility

Inclusion Criteria:

• ASAI-III patients undergoing laparoscopic nephrectomy
• 18<BMI<40

Exclusion Criteria:

• infection at the block site
• coagulation disorder
• pregnancy
• kidney failure
• liver failure
• heart failure
• allergy to local anesthetics
• patient refusal

Related Conditions & MeSH terms

• Acute Pain
• Analgesia, Patient-Controlled
• Pain, Postoperative

Intervention

Procedure:
• lateral tap block
In the axial plane on the midaxillary line between the subcostal margin and the iliac crest with a linear probe using a 12 cm insulated nerve block needle is advanced in planely from skin, external, and internal oblique muscles to the target of fascial plane between the internal oblique and the transversus abdominis muscles.
• posterior tap block
In the axial plane on the midaxillary line a linear probe using a 12 cm insulated nerve block needle is advanced posteriorly to the most posterior limit of the TAP between the internal oblique and transversus abdominis muscles.

Locations

Country	Name	City	State
Turkey	Ankara City Hospital,Bilkent	Ankara	Cankay

Sponsors (1)

Lead Sponsor	Collaborator
Ankara City Hospital Bilkent

Country where clinical trial is conducted

Turkey, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Visual analog pain scale 0	Patients will be asked about the severity of pain. They will be told that 0 = no pain, 10 = severe pain, and they will be asked to determine a number between 0 and 10 for the severity of pain.	at the PACU arrival
Primary	Visual analog pain scale 1	Patients will be asked about the severity of pain. They will be told that 0 = no pain, 10 = severe pain, and they will be asked to determine a number between 0 and 10 for the severity of pain.	Postoperative first hour
Primary	Visual Analog Pain scale 2	Patients will be asked about the severity of pain. They will be told that 0 = no pain, 10 = severe pain, and they will be asked to determine a number between 0 and 10 for the severity of pain.	Postoperative second hour
Primary	Visual analog pain scale 6	Patients will be asked about the severity of pain. They will be told that 0 = no pain, 10 = severe pain, and they will be asked to determine a number between 0 and 10 for the severity of pain.	Postoperative sixth hour
Primary	Visual Analog Pain scale 12	Patients will be asked about the severity of pain. They will be told that 0 = no pain, 10 = severe pain, and they will be asked to determine a number between 0 and 10 for the severity of pain.	Postoperative 12. hour
Primary	Visual Analog Pain scale 18	Patients will be asked about the severity of pain. They will be told that 0 = no pain, 10 = severe pain, and they will be asked to determine a number between 0 and 10 for the severity of pain.	Postoperative18. hour
Primary	Visual Analog Pain scale 24	Patients will be asked about the severity of pain. They will be told that 0 = no pain, 10 = severe pain, and they will be asked to determine a number between 0 and 10 for the severity of pain.	Postoperative 24. hour
Primary	opioid comsuption	Patients will be asked about the severity of pain. They will be told that 0 = no pain, 10 = severe pain, and they will be asked to determine a number between 0 and 10 for the severity of pain.	Within 24 hours postoperatively