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Alveolar Bone Loss clinical trials

View clinical trials related to Alveolar Bone Loss.

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NCT ID: NCT04297813 Recruiting - Clinical trials for Alveolar Bone Atrophy

Efficacy in Alveolar Bone Regeneration With Autologous MSCs and Biomaterial in Comparison to Autologous Bone Grafting

Maxibone
Start date: March 2020
Phase: Phase 3
Study type: Interventional

A randomized controlled clinical multi center trial to assess the efficacy of a combination of autologous mesenchymal stem cells and biomaterial in jaw bone regeneration prior to dental implant placement in comparison to standard autologous bone block grafting.

NCT ID: NCT04262999 Recruiting - Alveolar Bone Loss Clinical Trials

Bone Mineral Density and Periodontal Status in Patients on Antiepileptic Drug

Start date: January 1, 2020
Phase:
Study type: Observational

Assessment of bone mineral density and periodontal parameters in patients with epilepsy. Comparative evaluation of bone mineral density and levels of marginal alveolar bone in patients with epilepsy on monotherapy, combination therapy, and systemically healthy individuals.Comparative evaluation of periodontal parameters in all the patients who are on monotherapy and combination therapy and in systemically healthy individuals.

NCT ID: NCT04229719 Recruiting - Alveolar Bone Loss Clinical Trials

Effect of Topical Melatonin Application on Dental Implant Osseointegration and Marginal Bone Level

Start date: November 1, 2019
Phase: Phase 3
Study type: Interventional

Background: Melatonin (N-acetyl-5-methoxy-tryptamine) is an indoleamine synthesized and secreted by the pineal gland and other organs, such as the retina, bone marrow, and intestines in a circadian pattern. Some authors claimed that Melatonin induces bone formation, increase bone density, and bone implant contact. According to animal and human studies the melatonin can be used topically during implant placement to increase bone implant contact and reduce marginal bone loss. Purpose: The aim of this study was to evaluate the effect of the topical administration of melatonin on osseointegration of dental implants and in minimize marginal bone loss. Materials and Methods: Twenty single-piece endosseous implants (Dentium Co, Korea) will use to restore missing lower teeth from canine to first molar area. The study will be split-mouth technique, each patient serve as his own control (served into 2 groups), the study side (topical application of melatonin in the implant side), and the control side (no melatonin in the other implant side of the same patients).The primary and secondary stability of dental implant will be evaluated by periotest M device and measure bone level as baseline immediately after implant placement and after 6 months follow up by CBCT.

NCT ID: NCT03997578 Recruiting - Periodontitis Clinical Trials

Non-incised Papillae Surgical Approach (NIPSA) and Connective Tissue Graft Plus Emdogain for Periodontal Defects

Start date: September 3, 2019
Phase: N/A
Study type: Interventional

The present study pretends to show the results of combining a modification of the Non-incised papillae surgical approach (NIPSA) attempting to improve the outcome in the treatment of teeth with advanced periodontal support loss.

NCT ID: NCT03978962 Recruiting - Alveolar Bone Loss Clinical Trials

Performance and Safety of the Resorbable Collagen Membrane "Ez Cure"

Start date: June 17, 2019
Phase:
Study type: Observational

The evaluation of the clinical data has demonstrated the conformity of the Resorbable Collagen Membrane (RCM), EZ CureTM, with the relevant essential requirements for its use in periodontal applications. The RCM is intended for Guided Tissue Regeneration (GTR) and Guided Bone Regeneration (GBR) procedures. It acts as a barrier against the migration of epithelial cells within the bone defect (performance) and thus complies with several surgical indications in the treatment of maxillofacial bone defects. It has been concluded that the risks associated with the use of this device are acceptable when weighted against the benefits to the patients. In order to improve the clinical data on the RCM, the manufacturer, Biomatlante, decided to assess that the performance and safety of the device are maintained until the reaching of its intended use. In this objective, the goal of this study will be to observe the following parameters: 1. Tissue regeneration (mucosa health on the site of implantation) 2. Safety (report of any adverse event) 3. Radiographic analysis of periodontal tissues

NCT ID: NCT03927937 Recruiting - Tooth Loss Clinical Trials

Tooth Autotransplantation and Bone Dimension Changes

Start date: December 5, 2018
Phase: N/A
Study type: Interventional

Tooth autotransplantation is a treatment option to replace tooth with imposible prognosis. In several cases the receipt site has a reduced bone dimension. This situation may be imposible the treatment with dental implants without bone reconstruction. Autotransplantation seem to improve the anatomic characteristic of the receipt site without any reconstruction approach. The aim of this study is to evaluate the bone dimension changes followed autotransplantation treatment.

NCT ID: NCT03914339 Recruiting - Clinical trials for Periodontal Bone Loss

Effect of Orthodontic Treatment on Periodontally Compromised Dentition- Randomised Control Trial

Start date: December 1, 2018
Phase: N/A
Study type: Interventional

The main aim of this prospective, randomized controlled clinical study is to: • To evaluate and compare the effect of a combined orthodontic -periodontal treatment protocol versus periodontal treatment alone on osseous and non -osseous parameters in periodontally compromised patients.

NCT ID: NCT03863249 Recruiting - Clinical trials for Chronic Periodontitis

Use of the xCELLigence System for Quantification of Bacterial Biofilm's Real Time Formation and Antibiotics Selection.

Start date: February 8, 2019
Phase: Phase 4
Study type: Interventional

The aim of the study is to develop an in vitro model of growth of oral biofilms, and validate xCELLigence system for the selection of an effective antibiotic treatment for each patient.

NCT ID: NCT03855852 Recruiting - Bone Loss, Alveolar Clinical Trials

Evaluation of Vertical Bone Gain After Ridge Augmentation With APRF & Xenograft Vs Collagen Membrane & Xenograft. RCT

Start date: February 1, 2019
Phase: N/A
Study type: Interventional

Comparative study for evaluation of vertical bone gain after one stage ridge augmentation with advanced platelet rich fibrin (A-PRF) and xenograft versus guided bone regeneration using collagen membrane and xenograft.

NCT ID: NCT03528330 Recruiting - Clinical trials for Dental Implant Failed

Clinical, Radiological and Microbiological Outcomes of Implants With Two Different Connection Configurations, a Split-mouth RCT.

Start date: January 8, 2018
Phase: N/A
Study type: Interventional

This study designed as a randomized controlled split-mouth trial will be conducted at the Dental Clinic of the University of Valencia. The aim will be to assess differences in clinical, radiological and microbiological outcomes between implants with 2 different connections: internal hexagon and conical connection. Following the premises, to minimize the bias related to prosthetic phase and maximize the effect of connections on MBL changes, a 1abutment-1time protocol will be used. The study hypothesis is that there will be no statistically significant differences between both implant connections.