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Alveolar Bone Loss clinical trials

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NCT ID: NCT06412705 Completed - Clinical trials for Vitamin D Deficiency

Vit D and Post-extractive Bone Turnover

Start date: October 2, 2023
Phase: N/A
Study type: Interventional

The aims of the study was to correlate the extent of the dimensional alveolar bone changes after tooth extraction and contextual guided bone regeneration with serum vit D levels in 14 patients. Moreover, at 4 months, a small bone sample was collected in order to correlate histological and immunohistochemical parameters of bone with vit D serum levels.

NCT ID: NCT06209905 Completed - Alveolar Bone Loss Clinical Trials

Khoury Technique Versus Titanium Reinforced PTFE Membrane in 3D Alveolar Bone Augmentation

Start date: November 1, 2021
Phase: N/A
Study type: Interventional

In patients with missed lower posterior teeth and resorbed lower jaw, the study aimed at restoring the jaw's height and width to accommodate placing dental implants. The study was designed as a clinical trial with two arms; control group and study group. In the control group, titanium-reinforced polytetrafluoroethylene (Ti PTFE) membrane was used to secure the grafted bone mixture in the recipient site. While in the study group, bone-plate technique (Khoury technique) for bone restoration was used to secure the grafted bone mixture as well. The donor bone was the lower jaw (for bone particles and bone-plate harvesting) and bovine bone particles mixed together to form the graft mixture. Patients were monitored for six months and assessed by X-rays. The outcome variables were volume and height of gained bone in cubic millimeters and millimeters, respectively.

NCT ID: NCT06177899 Completed - Alveolar Bone Loss Clinical Trials

A Novel Approach for Horizontal Augmentation: A Split Box

Start date: January 20, 2023
Phase:
Study type: Observational

The goal of this clinical study is to investigate the effectiveness of the split-box technique in systemically healthy, non-smoking, over 18 years of age, participants with narrow crests (<5mm bone width) and adequate bone height (>12mm). The main questions it aims to answer are: - The primary objective of the present study is to investigate the effectiveness of the split-box technique by evaluating the change in width and height of the alveolar bone. - The secondary objective is to evaluate the superiority of the split-box technique and its modifications in terms of the amount of bone gain. According to the 3D topography of the alveolar ridge of the patients before augmentation, split box or one of its modifications, reverse split box or sliding split box techniques were selected and applied. (split box was applied if the bone thickness was more than 3 mm at the top of the crest and did not increase towards the lower border at the alveolar bone, reverse split box technique was applied if the bone thickness was more than 3 mm at the top of the crest and increased towards the lower border at the alveolar bone, sliding split box was applied if the bone thickness was less than 3 mm at the top of the crest but the bone thickness increases towards the lower border at the alveolar bone.)

NCT ID: NCT06176014 Completed - Alveolar Bone Loss Clinical Trials

Effect of Using (PEKK) Framework Versus (Co- Cr) Framework on The Bone of Mandibular Implant Supported Hybrid Prostheses

Start date: June 8, 2021
Phase: N/A
Study type: Interventional

the purposse of the study To evaluate the effect of implant supported hybrid prostheses on the bone of the supporting structure of edentulous mandible using Polyetherketoneketone (PEKK) framework versus cobalt chromium framework. fourteen female patients with lower single edentulous ridges are chosen with adequate dental hygiene, enough interarch space and free of systemic diseases and parafunctional habits. Patients who received new single dentures are randomly allocated into each group using computer software program and five intraforaminal implants were inserted parallel using surgical guide.

NCT ID: NCT06131541 Completed - Peri-Implantitis Clinical Trials

Ridge Splitting With Implant Placement Using Autogenous Tooth Graft

Start date: August 15, 2022
Phase: N/A
Study type: Interventional

The aim of this study is to evaluate the radiographic and the clinical outcomes of application of the alveolar ridge splitting (ARS) in combination with ATG, associated with immediate implant placement versus ARS in combination with autogenous bone graft, associated with immediate implant placement in patients with horizontal bony insufficiency of alveolar ridges.

NCT ID: NCT05811741 Completed - Alveolar Bone Loss Clinical Trials

Impact of Mandibular Canal Trajectory on Paresthesia After Inferior Alveolar Nerve Lateralization

Start date: June 1, 2016
Phase:
Study type: Observational

This prospective cohort study aims to investigate the relationship between mandibular canal trajectory and the duration of postoperative paresthesia in patients undergoing inferior alveolar nerve lateralization. The study will assess mandibular canal trajectory using anatomic factors and evaluate nerve sensory function using subjective and objective tests. Implant success criteria will also be assessed. The study will be conducted on patients who underwent IANL due to mandibular atrophy and were unable to receive standard or short implant placement. Data will be collected at regular follow-up visits up to 1-year post-surgery.

NCT ID: NCT05685576 Completed - Clinical trials for Alveolar Process Atrophy

Evaluation of a Combined Ridge Expansion Technique With Simultaneous Dental Implant Placement

Start date: March 25, 2022
Phase: N/A
Study type: Interventional

Patients with long span, narrow edentulous ridge in the posterior mandible underwent piezotomed ridge splitting and osseodensification with simultaneous implant placement.

NCT ID: NCT05640284 Completed - Alveolar Bone Loss Clinical Trials

Evaluation of the Effect of Periimplant Soft Tissue Phenotype on Marginal Bone Loss

Start date: December 2, 2022
Phase:
Study type: Observational

The goal of this clinical trial to test the effect of periimplant soft tissue phenotype in the participants with implant placed and at least 1 year after implant loading. The main questions it aims to answer are: 1. Is keratinized mucosal thickness (KMT) important in early marginal bone loss and peri implant health? 2. Is keratinized gingival width (KGW) important in early marginal bone loss and and peri implant health? The researchers plan to include 80 implants in the study. These 80 implants will be divided into 2 groups in 2 different ways according to their KMT and KGW on their buccal surfaces: KMT ≥2 mm are included in the adequate KMT, and those with KMT<2 mm are in the insufficient KMT group. Those with KGW≥2 mm are adequate KGW, those with KGW<2 mm are adequate KGW. The researchers will assess marginal bone loss around the implant using radiographs and collect peri-implant crevicular fluid (PICF) using paper strips. Another researchers will measure the Receptor Activator Of Nuclear Factor-Kappa B Ligand (RANKL), Osteoprotegerin (OPG), Tumor Necrosis Factor Alpha (TNF-α), MicroRNA-223 (MiRNA-223), MicroRNA-27a (MiRNA-27a) levels in the collected PICF. They will compare radiographic bone loss and biomarker levels in groups.

NCT ID: NCT05631600 Completed - Clinical trials for Periodontal Diseases

Manuka Honey as an Adjunct to Non-surgical Periodontal Therapy: Clinical Study

Start date: September 11, 2017
Phase: Phase 2/Phase 3
Study type: Interventional

The goal of this split-mouth clinical trial is to evaluate the effects of Manuka honey applied into periodontal pockets after initial periodontal therapy (NSPT) in the treatment of stage 3 periodontitis. The main question it aims to answer is: • does the adjunct of Manuka honey improve the outcome of the non-surgical periodontal treatment. The intervention in this study was conducted in a split-mouth design, meaning that after completing the NSPT for each subject, Manuka honey was administered as an adjunct to the periodontal treatment in two randomly selected quadrants of the oral cavity around the teeth with a specially designed cannula. This was followed by oral hygiene instructions and training. The home-performed oral hygiene procedures were focused on interdental cleaning using dental floss and toothbrushing with regular fluoride-containing toothpaste. The subjects were also instructed not to use any form of oral antiseptic (e.g., chlorhexidine) or antibiotic during the follow-up period.

NCT ID: NCT05612737 Completed - Bone Loss, Alveolar Clinical Trials

Evaluation of a Novel Horizontal Ridge Augmentation Technique in Dentistry

Start date: October 1, 2019
Phase: N/A
Study type: Interventional

This case series aimed to assess the efficacy of a novel horizontal ridge augmentation modality using histomorphometry and Raman spectroscopy. Combinations of "sticky bone" and tenting screws without autologous bone were used as augmentative materials.