A Study of ELX-02 in Patients With Alport Syndrome

Status Recruiting

Clinical Trial Summary

This is a Phase 2 open label pilot study to evaluate the safety and efficacy of subcutaneously administered ELX-02 in patients with X-linked or autosomal recessive Alport Syndrome with Col4A5 and Col4A3/4 nonsense mutation. In total, up to 8 participants, with a minimum of 3 adults, will be enrolled in the trial. The study will be comprised of the following periods for each participant: - a Screening period of up to 6 weeks (42 days) - a total Treatment Period of 8 weeks (60 days) - a safety/efficacy Follow-up Period of 12 weeks (90 days) after the last treatment The Treatment Period will be a treatment of ELX-02 0.75 mg/kg SC QD for 8 weeks.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT05448755
Study type	Interventional
Source	Eloxx Pharmaceuticals, Inc.
Contact	Eloxx Pharmaceuticals
Phone	+1(781) 577-5300
Email	info@eloxxpharma.com
Status	Recruiting
Phase	Phase 2
Start date	November 28, 2022
Completion date	May 30, 2023

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See also
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