Human Urine Sample Collection for Alport Nephropathy Biomarker Studies

Status Terminated

Clinical Trial Summary

This is a prospective cross-sectional, observational, single-center study of Alport patients, in which a single, first morning voided urine collection will be acquired and used to validate assays of urine biomarkers that reflect changes in glomerular protein filtration barrier function.

The purpose of this study is to identify biomarkers indicative of changes in glomerular filtration function that occur during the course of proteinuric renal diseases such as Alport nephropathy.

Clinical Trial Description

n/a

Study Design

Observational Model: Cohort, Time Perspective: Cross-Sectional

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT01602835
Study type	Observational
Source	Novartis
Contact
Status	Terminated
Phase	N/A
Start date	September 2012
Completion date	May 2013

View Details

See also
Status	Clinical Trial	Phase
Completed	`NCT01696253` - Multi-center Controlled Clinical Trials in Alport Syndrome-A Feasibility Study
Recruiting	`NCT00481130` - Alport Syndrome Treatments and Outcomes Registry
Recruiting	`NCT05687474` - Baby Detect : Genomic Newborn Screening
Recruiting	`NCT06065852` - National Registry of Rare Kidney Diseases
Recruiting	`NCT05448755` - A Study of ELX-02 in Patients With Alport Syndrome	Phase 2
Recruiting	`NCT06274489` - A Study to Evaluate Setanaxib in Patients With Alport Syndrome	Phase 1/Phase 2
Terminated	`NCT02855268` - Study of Lademirsen (SAR339375) in Patients With Alport Syndrome	Phase 2
Recruiting	`NCT06226896` - Effects of Dapagliflozin on Progression of Alport Syndrome
Recruiting	`NCT05927467` - Eurbio-Alport (RaDiCo Cohort) (RaDiCo Eurbio-Alport)
Terminated	`NCT03749447` - An Extended Access Program for Bardoxolone Methyl in Patients With CKD (EAGLE)	Phase 3
Completed	`NCT03019185` - A Phase 2/3 Trial of the Efficacy and Safety of Bardoxolone Methyl in Patients With Alport Syndrome - CARDINAL	Phase 2/Phase 3
Completed	`NCT01705132` - Urinary Biomarkers of the Progression of Alport Kidney Disease	N/A
Recruiting	`NCT05267262` - Study to Evaluate R3R01 in Patients With Alport Syndrome and Patients With Focal Segmental Glomerulosclerosis	Phase 2
Completed	`NCT00622544` - A Prospective Study of Microalbuminuria in Untreated Boys With Alport Syndrome
Recruiting	`NCT02378805` - European Alport Therapy Registry - European Initiative Towards Delaying Renal Failure in Alport Syndrome
Not yet recruiting	`NCT05655728` - Treatment With Metformin in Chinese Children With Alport Syndrome	Phase 4
Completed	`NCT00309257` - Effects of an Intensified Treatment With ACE-I,ATA II and Statins in Alport Syndrome	Phase 2
Not yet recruiting	`NCT05133050` - Safety and Efficacy of ACEI in Alport Syndrome Patients With COL4A3/COL4A4/COL4A5 Variants	N/A
Recruiting	`NCT04947813` - Genotype-Phenotype Correlations in Patients With Alport Syndrome
Active, not recruiting	`NCT04573920` - Atrasentan in Patients With Proteinuric Glomerular Diseases	Phase 2