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Alopecia Areata clinical trials

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NCT ID: NCT03831334 Active, not recruiting - Clinical trials for Permanent Chemotherapy-induced Alopecia

Effect of Low-Dose Oral Minoxidil as Treatment of Permanent Chemotherapy-Induced Alopecia

Start date: April 9, 2019
Phase: Early Phase 1
Study type: Interventional

An open label, pilot study involving the use of low dose oral minoxidil to treat permanent chemotherapy-induced alopecia.

NCT ID: NCT03570749 Active, not recruiting - Alopecia Areata Clinical Trials

A Study of Baricitinib (LY3009104) in Participants With Severe or Very Severe Alopecia Areata

BRAVE-AA1
Start date: September 24, 2018
Phase: Phase 2/Phase 3
Study type: Interventional

This study is designed to select up to two doses of baricitinib (referred to as low dose and high dose) and assess their efficacy and safety for the treatment of severe or very severe alopecia areata. An additional subpopulation of 60 participants in the US will enroll in the open-label addenda.

NCT ID: NCT02999737 Active, not recruiting - Clinical trials for Androgenetic Alopecia

Comparing Different Platelet Rich Plasma (PRP) Treatment Regimens for Management of Androgenic Alopecia

Start date: November 2016
Phase: Phase 4
Study type: Interventional

The injection of autologous platelet rich plasma (PRP) is a relatively novel therapy, generating interest across a wide variety of medical specialties, such as orthopedics, dentistry, ophthalmology, and dermatology. Several recently published studies have demonstrated efficacy in treating androgenetic alopecia (aka male or female patterned hair loss), but each varies in the treatment protocol, and there is no evidence-based data to date guiding the dosing parameters of and intervals between injection sessions. We propose a single-center, single-blinded randomized pilot trial to investigate the most beneficial number and frequency ('schedule') of necessary PRP injections in men and women with androgenetic alopecia.

NCT ID: NCT02530177 Active, not recruiting - Clinical trials for Non-Metastatic Breast Cancer

Study of Chemotherapy-Induced Hair Changes and Alopecia, Skin Aging and Nail Changes in Women With Non-Metastatic Breast Cancer

Start date: August 19, 2015
Phase:
Study type: Observational

The purpose of this study is to see how many patients develop hair, skin and nail changes due to cancer treatments. The investigators would like to study the clinical factors, genetic markers, and impact on patients' health-related quality of life to learn more about who is at greater risk. We trust that the study will improve our understanding of how cancer patients feel about their skin, hair, and nail conditions. This information will help us determine the burden on breast cancer patients and survivors. It will also help us learn how to prevent these conditions and it may improve the way we treat them and counsel patients.

NCT ID: NCT02528552 Active, not recruiting - Clinical trials for Androgenetic Alopecia

Treatment of Androgenetic Alopecia in Males With Theradomeā„¢ LH80 PRO

Start date: August 2015
Phase: Phase 2
Study type: Interventional

This is a prospective, randomized double-blind, multi-center study to evaluate the efficacy of low level laser therapy over-the-counter at home device Theradome LH80 PRO, compared to SHAM for promoting hair growth in males diagnosed with androgenetic alopecia, and a usability study to assess subject ability to self-assess hair loss and understanding use of the device.

NCT ID: NCT01986140 Active, not recruiting - Breast Cancer Clinical Trials

Scalp Cooling to Prevent Chemo-induced Hair Loss

SCALP
Start date: May 15, 2014
Phase: N/A
Study type: Interventional

Determine that the Orbis Paxman Hair Loss Prevention System is safe and effective in reducing chemotherapy-induced alopecia in woman with breast cancer undergoing neoadjuvant or adjuvant chemotherapy.

NCT ID: NCT01831024 Active, not recruiting - Breast Cancer Clinical Trials

Efficacy and Safety of Dignicap System for Preventing Chemotherapy Induced Alopecia

Start date: July 2013
Phase: N/A
Study type: Interventional

The efficacy and safety of the Dignicap System to prevent chemotherapy induced alopecia will be evaluated in women with early breast cancer undergoing adjuvant or neoadjuvant chemotherapy regimens. The scalp cold cap will be applied at each chemotherapy cycle. Hair loss will be evaluated by patient self assessment of 5 standardized photographs taken prior to each chemotherapy cycle. A concurrent control group not using a cold cap will also be evaluated.

NCT ID: NCT01655108 Active, not recruiting - Clinical trials for Female Pattern Alopecia

Efficacy and Safety of Mesotherapy With Minoxidil 0.5%/2ml for Androgenetic Alopecia in Female Patients

Start date: March 2012
Phase: Phase 3
Study type: Interventional

This study aims to investigate the effectiveness and safety of mesotherapy for the treatment of female pattern alopecia. - Sixty female subjects between 18 and 65 years diagnosed with female pattern hair loss will undergo mesotherapy sessions weekly for ten weeks. - One group will receive 0.5%/2ml minoxidil application and a control group will receive application of placebo (saline 0.9%). - Biopsy of the scalp, trichogram and trichoscopy (Fotofinder) will be performed before and 08 weeks after treatment as a method objective evaluation of the response

NCT ID: NCT01644422 Active, not recruiting - Clinical trials for Androgenetic Alopecia

Study To Determine Safety & Efficacy Of Autologous Human Platelet Lysate in Androgenetic Alopecia After Hair Transplant

Start date: January 2012
Phase: Phase 1/Phase 2
Study type: Interventional

This is a multicentre, open label, randomized, pilot study to evaluate safety and efficacy of Human Platelet Lysate (HPL) in subjects with Androgenetic Alopecia undergoing hair transplantation. The study is being conducted at 2 centers in India. The primary endpoints are Increase in Hair Follicle viability after transplant, Improvement in Caliber & Density of hair and Improvement in Photographic assessment from randomization to end of study. The secondary endpoints are Physicians and Patients self assessment score.

NCT ID: NCT01643629 Active, not recruiting - Clinical trials for Androgenetic Alopecia

A Study to Determine the Safety and Efficacy of Autologous Human Platelet Lysate for Treatment of Androgenetic Alopecia

Start date: January 2012
Phase: Phase 1/Phase 2
Study type: Interventional

This is a multicentre, open label, randomized, pilot study to evaluate safety and efficacy of Human Platelet Lysate (HPL) in subjects with Androgenetic Alopecia. The study is being conducted at 2 centers in India. The primary endpoints are Improvement in Caliber & Density of hair and Improvement in Photographic assessment from randomization to end of study. The secondary endpoints are Physicians and Patients self assessment score.