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Clinical Trial Summary

The incidence of provoked and unprovoked seizures is known to increase with advancing age. Eslicarbazepine acetate (ESL) is one of the third generation of antiepileptic drugs (AEDs) that have been developed in the last ten years with a favorable safety profile. ESL is approved in Europe and the USA as adjunctive or monotherapy in adults with partial-onset seizures. Nevertheless, retrospective data in monotherapy condition in the elderly epileptic population are sparse. The aim of the ZEBRE study is to evaluate the efficacy and the safety of ESL in elderly epileptic patients (> 65 years). The completion of this study will provide crucial information on the most appropriate ESL treatment for elderly patients suffering from partial seizures.


Clinical Trial Description

The ZEBRE (ZEBinix® Retention rate in epilepsy in Elderly patients) study is a prospective, multicenter, descriptive study. ESL will be prescribed according to the usual care. Posology and method of administration of ESL are defined by the summary of product characteristics. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT04221282
Study type Observational
Source Centre Hospitalier Saint Joseph Saint Luc de Lyon
Contact Adrien DIDELOT, MD, PhD
Phone 0033478616172
Email adidelot@ch-stjoseph-stluc-lyon.fr
Status Recruiting
Phase
Start date April 1, 2019
Completion date September 30, 2020

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