Comparison of Different HES Coload Volumes on the 90% ED of Norepinephrine

Status Completed

Clinical Trial Summary

The purpose of this study is to investigate the effect of different 6% hydroxyethyl starch (130/0.4) coload volumes on the 90% effective dose of norepinephrine infusion prophylaxis for hypotension during spinal anesthesia for cesarean section.

Clinical Trial Description

Post-spinal anesthesia hypotension is a frequent complication during spinal anesthesia for cesarean section. The incidence of post-spinal anesthesia hypotension is as high as 62.1-89.7% if prophylactic measures are not taken. Coload has been highly demonstrated for prevention and/or treatment of post-spinal anesthesia hypotension. In addition, there's some evidence that prophylactic infusion of norepinephrine could effectively reduce the incidence of post-spinal anesthesia hypotension in parturients undergoing cesarean section. The purpose of this study is to investigate the effect of different 6% hydroxyethyl starch (130/0.4) coload volumes on the 90% effective dose of norepinephrine infusion prophylaxis for hypotension during spinal anesthesia for cesarean section. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT05712018
Study type	Interventional
Source	General Hospital of Ningxia Medical University
Contact
Status	Completed
Phase	N/A
Start date	October 20, 2023
Completion date	January 23, 2024

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